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The Role of Hippo/YAP Signaling in Vascular Remodeling and Related Diseases

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Vascular remodeling is a vital process of a wide range of cardiovascular diseases and represents the altered structure and arrangement of blood vessels. The Hippo pathway controls organ size by regulating cell survival, proliferation and apoptosis. Yes-associated protein (YAP), a transcription coactivator, is a downstream effector of the Hippo pathway. Emerging evidence supports that the Hippo/YAP pathway plays an important role in vascular-remodeling and related cardiovascular disease

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: .,

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English

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NONE

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Oncology

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