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Ketoprofen Pharmacokinetics, Efficacy, and Tolerability in Pediatric Patients


The NSAID ketoprofen is used widely in the management of inflammatory and musculoskeletal
conditions, pain, and fever in children and adults. Pharmacokinetic studies show that drug exposure after
a single intravenous dose is similar in children and adults (after dose normalization), and thus similar mg /kg
bodyweight dosing may be used in children and adults. Ketoprofen crosses the blood-brain barrier and
therefore has the potential to cause central analgesic effects.


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English
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NONE
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Pediatr Drugs 2010; 12 (5): 313-329
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