We developed a two-stream, Apache Solr-based information retrieval system in response to the bioCADDIE 2016 Dataset Retrieval Challenge. One stream was based on the principle of word embeddings, the other was rooted in ontology based indexing. Despite encountering several issues in the data, the evaluation procedure and the technologies used, the system performed quite well. We provide some po…
Community acquired pneumonia (CAP) is a leading cause of childhood morbidity worldwide. Because of the rising antimicrobial resistance rates and adverse effects of childhood antibiotic use on the developing microbiome, rational prescribing of antibiotics for CAP is important. This review summarizes and critically reflects on the available evidence for the epidemiology, etiology and antimicrobia…
Pneumonia continues to be a leading cause of hospitalization and mortality. Implementation of health information technology (HIT) can lead to cost savings and improved care. In this review, we examine the literature on the use of HIT in the management of community-acquired pneumonia. We also discuss barriers to adoption of technology in managing pneumonia, the reliability and quality of elec…
The American and European expert documents recommend transcatheter aortic valve replacement (TAVR) for inoperable or high-surgical-risk patients with severe aortic stenosis. In comparison, efficacy of TAVR is relatively less studied in low- to intermediate-surgical-risk patients. We sought to discover whether TAVR can be as effective as surgical aortic valve replacement (SAVR) in low- to inter…
Aortic Valve Disease (AVD) is the most common Valvular Heart Disease (VHD), affecting millions of people worldwide. Severe AVD is treated in most cases with prosthetic aortic valve replacement, which involves the substitution of the native aortic valve with a prosthetic one. In this review we will discuss the different types of prosthetic aortic valves available for implantation and the challe…
Aborsi spontan adalah pelepasan produk konsepsi dengan alasan tertentu pada atau sebelum usia kehamilan 20 minggu atau berat badan janin kurang dari 500 gram yang terjadi secara tidak sengaja. Kasus abortus spontan yang terjadi di RSUD Kabupaten Temanggung mengalami tren meningkat pada tiga tahun terakhir yaitu 7 abortus spontan per 100 kelahiran hidup pada tahun 2013, 17 abortus spontan per 10…
Brucella abortus is an intracellular pathogen which can infect and persist in host cells through multiple interactions. Above all, its interaction to host cell receptor is important to understand the pathogenic mechanisms of B. abortus. Accordingly, we demonstrated that platelet-activating factor receptor (PAFR) affects host cell response against B. abortus infection
A 30-year-old male patient presented with headache and incidental finding of aright ethmoidal sinus ossifying fibroma by paranasal-sinuses CT scan and MRI of the face. A flexiblefiber-optic nasal endoscopy examination revealed a right side fullness. A non-contrasted CT scan of theparanasal sinus showed hyperdense lesion at the right ethmoid air cells. Functional endoscopic sinussurgery was perf…
Presumptive diagnosis is established by clinical examination and CT scan (location, oval-shaped mass, heterogeneous tumor with a thin bony rim). Definitive diagnosis is founded on histological examination (psammomatous bodies, osteoblastic rim, trabecular bone). Treat- ment in paranasal sinus OF is surgical, preferentially on an endoscopic approach. Resection should be as complete as possib…
Advances in medical care, particularly cardiac surgery, over the past half century have led to significant improvements in outcomes for children with chronic medical conditions. Children with structural heart defects, both genetic and acquired, have seen a profound improvement in survival.1,2 With anticipated adult survival for most children with cardiovascular conditions, an increasing number…