Patients with end-stage renal disease on dialysis (ESRD-HD) have an increased risk of sepsis and sepsis-related mortality. Professional society and government guidelines recommend weight-based initial IV fluid resuscitation targets as part of sepsis care bundles; however, there are no specific recommendations for patients with sepsis and ESRD-HD. While higher volumes of administered fluids have…
Brucella abortus is an intracellular pathogen which can infect and persist in host cells through multiple interactions. Above all, its interaction to host cell receptor is important to understand the pathogenic mechanisms of B. abortus. Accordingly, we demonstrated that platelet-activating factor receptor (PAFR) affects host cell response against B. abortus infection