H1-receptor antagonists are effective for the treatment of seasonal allergic rhinitis. In rare circumstances, some second-generation H1-receptor antagonists have been associated with prolongation of the corrected QT interval (QTc), thus increasing the risk of ventricular arrhythmias. Fexofenadine HCl, the carboxylic acid metabolite of terfenadine, is a new second-generation antihistamine that i…
In this issue, we continue our reviews of recent advances and novel approaches in paediatric cardiology, focusing on the amazing advances in understanding the genetics of childhood cardiovascular disease. It has now been 27 years since the initiation of the Human Genome Project, and 14 years since its completion.