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Brief Review on the Causes, Diagnosis and Therapeutic Treatment of Gastritis …
Gastritis represent a state of inflammation, irritation, or erosion of the stomach lining which may occur suddenly (acute) or gradually (chronic). Generally there is no universally accepted classification of gastritis and early classification was based mainly on the morphology, but recently pathogenic mechanisms have also been incorporated. The gastric mucosa is continuously exposed to many nox…
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Chronic gastritis
Prevalence of chronic gastritis has markedly declined in developed populations during the past decades. However, chronic gastritis is still one of the most common serious pandemic infections with such severe killing sequelae as peptic ulcer or gastric cancer. Globally, on average, even more than half of people may have a chronic gastritis at present. Helicobacter pylori infection in childhoo…
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Helicobacter pylori associated chronic gastritis, clinical syndromes, precanc…
Helicobacter pylori (H. pylori ) infection is well known to be associated with the development of precancerous lesions such as chronic atrophic gastritis (AG), or gastric intestinal metaplasia (GIM), and cancer. Various molecular alterations are identified not only in gastric cancer (GC) but also in precancerous lesions. H. pylori treatment seems to improve AG and GIM, but still remains contro…
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New Approaches in Gastritis Treatment
Gastritis is an inflammation of the stomach lining, which is fairly common and could have different causes. Many kind of agents may lead the stomach into an inflamed statement; in first place, it could be due to non-steroidal anti-inflammatory drugs (NSAID) such as aspirin, ibuprofen, naproxen, etc. (Fig. 1), which are used in different treatments to calm down some specific illness, e.g. rheum…
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Potential Benefits of pH 8.8 Alkaline Drinking Water as an Adjunct in the Tre…
Unlike conventional drinking water, pH 8.8 alkaline water instantly denatures pepsin, rendering it permanently inactive. In addition, it has good acid-buffering capacity. Thus, the consumption of alkaline water may have therapeutic benefits for patients with reflux disease
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A Comparison of AlkalineWater and Mediterranean Diet vs Proton Pump Inhibitio…
Laryngopharyngeal reflux (LPR) is a common disorder with protean manifestations in the head and neck. In this retrospective study, we report the efficacy of a wholly dietary approach using alkaline water, a plant-based, Mediterranean-style diet, and standard reflux precautions compared with that of the traditional treatment approach of proton pump inhibition (PPI) and standard reflux precaut…
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Evaluation and management of variceal bleeding
Acute variceal bleeding is one of the most fatal complications of cirrhosis and is responsible for about one-third of cirrhosis-related deaths.Therefore,every effort should be made to emergently resuscitate the patients,start pharma-cotherapy as soon as possible and do endoscopic therapy in a timely manner. Despite there cent advances in treatment, mortality rate is still high.We provide a comp…
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Radiation Colitis and Proctitis
Radiation therapy is commonly utilized as a major component in the treatment of pelvic malignancy. Unfortunately, secondary toxicity to the lower gastrointestinal tract can occur. This most commonly affects the rectum, although injuries to the colon and small intestine are not uncommon. The presentation can be acute or chronic, and different mechanisms are responsible for each. Symptomatology i…
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Review article: comparison of the pharmacokinetics, acid suppression and effi…
Proton pump inhibitors have dramatically in¯uenced the management of acid-peptic disorders in recent years. They all have a broadly similar mechanism of action and are extensively metabolized in the liver via cytochromes P450 2C19 and 3A4. There is some variation in their potential for drug interactions due to differences in enzyme inhibition. Relatively few serious adverse effects have been …
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Design of Freeze-Drying Processes for Pharmaceuticals: Practical Advice
Design of freeze-drying processes is often approached with a “trial and error” experimental plan or, worse yet, the protocol used in the first laboratory run is adopted without further attempts at optimization. Consequently, commercial freeze-drying processes are often neither robust nor efficient. It is our thesis that design of an “optimized” freeze-drying process is not particularly …
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