Early Administration of Antibiotics for Suspected Sepsis

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Recent advances in the management of radiation colitis

Radiation colitis, an insidious, progressive disease of increasing frequency, develops 6 mo to 5 years after regional radiotherapy for malignancy, owing to the deleterious effects of the latter on the colon and the small intestine. When dealing with radiation colitis and its complications, the most conservative modality should be employed because the areas of intestinal injury do not tend to h…

Necrotizing fasciitis: Classification, diagnosis, and management

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Defining of initial antibiotic treatment of pleural empyema

Parapneumonic effusions are often complications of bacterial pneumonia, occurring in 5-50% patients and in 15% cases it can progress into pleural empyema. Pleural empyema treatment includes drainage of pus, re-expansion of lung by using appropriate antibiotics. Initial antibiotics treatment of pleural empyema is usually started with antibiotics that are resistant to causes found in isolates.

Sepsis

Sepsis is a clinical syndrome that requires prompt recognition andrncontrol in order to optimize clinical outcomes in patients. It is very relevantrnto surgical practice, as it can affect perioperative patients andrnthose recovering on surgical wards. A working knowledge of sepsisrnis essential to any medical or surgical practitioner, and here werncover the topic with relevance to surgery and t…

Type 2 Myocardial Infarction : JACC Review Topic of the Week

Acute myocardial infarction (MI) can occur from increased myocardial oxygen demand and/or reduced supply in the absence of acute atherothrombotic plaque disruption; a condition called type 2 myocardial infarction (T2MI). As with any MI subtype, there must be clinical evidence of myocardial ischemia to make the diagnosis. This condition is increasingly diagnosed due to the increasing sensitiv…

Radiation Colitis and Proctitis

Radiation therapy is commonly utilized as a major component in the treatment of pelvic malignancy. Unfortunately, secondary toxicity to the lower gastrointestinal tract can occur. This most commonly affects the rectum, although injuries to the colon and small intestine are not uncommon. The presentation can be acute or chronic, and different mechanisms are responsible for each. Symptomatology i…

Evaluasi Penggunaan Antibiotik dan Profil Kuman pada Seksio Sesarea di Rumah …

Infeksi Luka Operasi (ILO) adalah salah satu komplikasi pembedahan yang paling umum terjadi di dunia, terutama di negara berkembang. Penggunaan antibiotik profilaksis sebelum operasi yang tepat dapat mengurangi ILO. Penelitian ini bertujuan untuk mengetahui profil penggunaan antibiotik dan kesesuaian penggunaan antibiotik pada seksio sesarea dengan peta kuman rumah sakit, Pedoman Penggunaan Ant…

Clinical Outcomes and Cost Minimization with an Alternative Dosing Regimen fo…

To compare outcomes and cost for the traditional United States Food and Drug Administration–approved dosing regimen for meropenem versus an alternative dosing regimen providing similar pharmacodynamic exposure with a lower total daily dose.

Safety Profile of Meropenem: a Review of Nearly 5,000 Patients Treated with M…

Meropenem is a parenteral carbapenem that has been used clinically since 1994. Since the first review of its safety profile in 1995, the patient database has increased substantially. This new safety analysis includes data from 46 clinical trials in hospitalized patients with serious bacterial infections. The additional data comprise patients with lower respiratory tract and intra-abdominal infe…