High-dose ceftriaxone for CNS infection administered as recommended by French guidelines in adults was well tolerated overall, suggesting these recommendations could be applied and generalized. In patients with advanced age or renal insufficiency, prescription should be done with caution and therapeutic drug monitoring could be useful.
Enteric fever (typhoid and paratyphoid fever) is caused by Salmonella enterica serovar Typhi (S. Typhi) and Salmonella enterica serovar Paratyphi (S. Paratyphi). S. Paratyphi A and B (and, uncommonly, S. Paratyphi C) cause a disease that is clinically indistinguishable from typhoid fever, particularly in parts of Asia.
Telah dilakukan penelitian pola penggunaan antibiotik profilaksis pada pasien bedah caesar (Seksio Sesare) di Rumah Sakit Pekanbaru Medical Center (PMC) tahun 2014. Tujuan penelitian ini untuk mengetahui pola penggunaan antibiotik profilaksis bedah sesar. Jenis penelitian yang dilakukan adalah penelitian observasional yang dirancang dengan studi deskriptif dengan cara melakukan kajian terhadap …
Infeksi nosokomial merupakan penyebab utama tingginya angka kesakitan dan kematian di dunia. Pada tahun 2002 CDC memperkirakan angka kejadian infeksi nosokomial di rumah sakit 1,7 juta orang dan sekitar 99.000 orang meninggal karena infeksi ini.Infeksi luka operasi (ILO) merupakan salah satu dari infeksi nosokomial mayoritas yang terjadi di rumah sakit. Penggunaan antibiotik profilaksis yang se…
Your doctor has determined that you have radiation colitis, an inflammation of the colon that occurs as a side effect of cancer radiation therapy to the abdomen or pelvis. The condition can arise from external radiation treatment delivered by a high energy X-ray machine or internal radiation therapy, which is delivered through small implants placed directly into or near the cancerous tumor
Radiation therapy is commonly utilized as a major component in the treatment of pelvic malignancy. Unfortunately, secondary toxicity to the lower gastrointestinal tract can occur. This most commonly affects the rectum, although injuries to the colon and small intestine are not uncommon. The presentation can be acute or chronic, and different mechanisms are responsible for each. Symptomatology i…
Infeksi Luka Operasi (ILO) adalah salah satu komplikasi pembedahan yang paling umum terjadi di dunia, terutama di negara berkembang. Penggunaan antibiotik profilaksis sebelum operasi yang tepat dapat mengurangi ILO. Penelitian ini bertujuan untuk mengetahui profil penggunaan antibiotik dan kesesuaian penggunaan antibiotik pada seksio sesarea dengan peta kuman rumah sakit, Pedoman Penggunaan Ant…
Multidrug-resistant Salmonella enterica subsp. enterica serovar Typhi (resistant to ampicillin, chloramphenicol and cotrimoxazole), was significantly reduced with the increased usage of fluoroquinolones and azithromycin. This has led to declining multidrug resistance rates in Indiawith increasing ciprofloxacin nonsusceptibility rates and clinical failures due to azithromycin. However, for the …
Ceftriaxone is a parenteral third-generation cephalosporin with a long elimination half-life which permits once-daily administration. It has good activity against Streptococcus pneumoniae, methicillin-susceptible staphylococci, Haemophilus influenzae, Moraxella catarrhalis and Neisseria spp. Although active against Enterobacteriaceae, the recent spread of derepressed mutants which hyperproduc…
To determine the safety of ceftriaxone in paediatric patients and systematically evaluate the categories and incidences of adverse drug reactions (ADRs) of ceftriaxone in paediatric patients