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Found 11 from your keywords: subject="Tensivask"
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Exforge® (amlodipine/valsartan combination) in hypertension: the evidence of…
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Krzesinski JM

This review analyses one of these strategies, which is the development of effective and safe combination therapy. Indeed, at least two antihypertensive agents are often needed to achieve blood pressure control. Exforge® (Novartis) is a new drug combination of the calcium channel blocker, amlodipine, and the angiotensin II receptor blocker, valsartan

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Pharmacokinetic and bioequivalence of two formulations of Valsartan/Amlodipin…
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Mei Y

Valsartan/amlodipine combination tablets can exert synergistic antihypertensive effects through different mechanisms, significantly lowering blood pressure while also addressing multiple risk factors and comorbidities in patients. This study designed a single-center, randomized, open-label, two-formulations, single-dose, three-cycle, three-sequence, partially repeated crossover controlled trial…

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Valsartan addition to amlodipine is more effective than losartan addition in …
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Fogari R

This study evaluated the effects on blood pressure (BP) of valsartan 160 mg or losartan 100 mg addition to amlodipine 5 mg in hypertensive patients.

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Improved Persistence to Medication, Decreased Cardiovascular Events and Reduc…
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Schmieder RE

Antihypertensive combination therapy reduces all-cause mortality and cardiovascular events when provided as single pill compared to identical drugs as multipills. This strongly supports the European Society of Cardiology/European Society of Hypertension and International Society of Hypertension guidelines recommending the use of a single-pill combination and thus should be more rigorously imple…

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Real-Life Safety and Effectiveness of Amlodipine/Valsartan Combination in the…
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Chazova IE

The aim of our study was to evaluate the safety and effectiveness of the free combination of amlodipine/valsartan in patients with arterial hypertension in a real-life setting

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Heart failure drug treatment
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Rossignol P

Heart failure is the most common cardiovascular reason for hospital admission for people older than 60 years of age. Few areas in medicine have progressed as remarkably as heart failure treatment over the past three decades. However, progress has been consistent only for chronic heart failure with reduced ejection fraction. In acutely decompensated heart failure and heart failure with preser…

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Atrial fibrillation and stroke: a practical guide
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Best JG

Neurologists and stroke physicians will be familiar with atrial fibrillation as a major cause of ischaemic stroke, and the role of anticoagulation in preventing cardioembolic stroke. However, making decisions about anticoagulation for individual patients remains a difficult area of clinical practice, balancing the serious risk of ischaemic stroke against that of major bleeding, particularly in…

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Outcomes in hypertensive patients at high cardiovascular risk treated with re…
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Julius S

The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial was designed to test the hypothesis that for the same blood-pressure control, valsartan would reduce cardiac morbidity and mortality more than amlodipine in hypertensive patients at high cardiovascular risk

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Effect of Amlodipine on the Progression of Atherosclerosis and the Occurrence…
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Pitt B

Amlodipine has no demonstrable effect on angiographic progression of coronary atherosclerosis or the risk of major cardiovascular events but is associated with fewer hospitalizations for unstable angina and revascularization.

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Effects of Different Blood Pressure–Lowering Regimens on Major Cardiovascul…
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Blood Pressure Lowering Treatment Trialists’ Collaboration

Blood pressure (BP) level is a major determinant of cardiovascular morbidity and mortality in individuals with diabetes mellitus. Several guidelines recommend lower BP goals and specific drug classes for these patients. The overviews reported herein were performed to formally compare the effects on cardiovascular events and death of different BP-lowering regimens in individuals with and withou…

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