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Differences in Blood Pressure in Infants after General Anesthesia compared to…
The General Anesthesia compared to Spinal anesthesia (GAS) study is a prospective randomized, controlled, multi-site, trial designed to assess the influence of general anesthesia (GA) on neurodevelopment at five years of age. A secondary aim obtained from the blood pressure data of the GAS trial is to compare rates of intraoperative hypotension after anesthesia and to identify risk factors for …
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Randomized, controlled trial comparing the effects of anesthesiawith propofol…
Pain is the primary complaint and the main reason for prolonged recovery after laparoscopic cholecystectomy. The authors hypothesized that patients undergoing laparoscopic cholecystectomy will have less pain four hours after surgery when receiving maintenance of anesthesia with propofol when compared to isoflurane, desflurane, or sevoflurane
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Clinical Research Methodology 3: Randomized Controlled Trials
Randomized assignment of treatment excludes reverse causation and selection bias and, in suffciently large studies, effectively prevents confounding. Well-implemented blinding prevents measurement bias. Studies that include these protections are called randomized, blinded clinical trials and, when conducted with suffcient numbers of patients, provide the most valid results. Although conceptuall…
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Experts’ guidelines of intubation and extubation of the ICU patient of Fren…
Intubation and extubation of ventilated patients are not risk-free procedures in the intensive care unit (ICU) and can be associated with morbidity and mortality. Intubation in the ICU is frequently required in emergency situations for patients with an unstable cardiovascular or respiratory system. Under these circumstances, it is a highrisk procedure with life-threatening complications (20–5…
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Hospital Operative Volume Is an Essential Quality Indicator for General Surge…
Within the growing geriatric population, there is an increasing need for emergency operations. Optimizing outcomes may require a structured system of surgical care based on key quality indicators. To investigate this, the present study sought to answer two questions. First, to what degree does hospital emergency operative volume impact mortality for geriatric patients undergoing emergency gener…
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Expanding the Scope of Quality Measurement in Surgery to Include Non-Operativ…
Patients managed non-operatively have been excluded from risk-adjusted benchmarking programs, including the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP). Consequently, optimal performance evaluation is not possible for specialties like emergency general surgery (EGS) where non-operative management is common. We developed a multi-institutional EGS clin…
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General surgery in Canada: current scope of practice and future needs
The scope of practice of general surgeons in Canada is highly variable. The objective of this study was to examine the demographic characteristics of general surgeons in Canada and compare surgical procedures performed across community sizes and specialties.
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Analysis of Infusion Patterns of Propofol and Remifentanil During Rigid Bronc…
We analyzed the dosage pattern of anesthetic drugs administered to maintain anesthesia during rigid bronchoscopy
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Inhalational Anaesthesia Versus Total Intravenous Anaesthesia During a Rigid …
General anaesthesia is routinely used for rigid bronchoscopy in paediatrics for different causes. Both methods of anaesthesia were used inhalational and total intravenous anaesthesia (TIVA
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Remifentanil-based total intravenous anesthesia for pediatric rigid bronchosc…
Laryngoscopy and stimuli inside the trachea cause an intense sympatho-adrenal response. Remifentanil seems to be the optimal opioid for rigid bronchoscopy due to its potent and short-acting properties. The purpose of this study was to compare bolus propofol and ketamine as an adjuvant to remifentanil-based total intravenous anesthesia for pediatric rigid bronchoscopy
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