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Cytokine storm in Covid-19-Immunopathological mechanisms, clinical considerat…
Cytokine storm is an acute hyperinflammatory response that may be responsible for critical illness inmany conditions including viral infections, cancer, sepsis, andmulti-organ failure. The phenomenon has been implicated in critically ill patients infected with SARS-CoV-2, the novel coronavirus implicated in COVID-19. Critically ill COVID-19 patients experiencing cytokine storm are believed to …
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Antioxidants in dermatology
The skin cells continuously produce, through cellular respiration, metabolic processes or under external aggressions, highly reactive molecules oxidation products, generally called free radicals. These molecules are immediately neutralized by enzymatic and non-enzymatic systems in a physiological and dynamic balance. In situations where this balance is broken, various cellular structures, such …
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Complementary and Alternative Medicine Use in Dermatology in the United States
Complementary and alternative medicine (CAM) has an increasing presence in dermatology. Complementary therapies have been studied in many skin diseases, including atopic dermatitis and psoriasis. Objectives: This study sought to assess oral CAM use in dermatology relative to medicine as a whole in the United States, using the National Ambulatory Medical Care Survey
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Potential applications of topical oxygen therapy in dermatology
Topical oxygen therapy is a cosmetic procedure that is becoming more and more popular in dermatology; however, only a few articles on this topic are present in the literature. In this work we report our group experience with oxygen therapy as an adjuvant treatment in various dermatological conditions.
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Pre-eclampsia: pathogenesis, novel diagnostics and therapies
Pre-eclampsia is a complication of pregnancy that is associated with substantial maternal and fetal morbidity and mortality. The disease presents with new-onset hypertension and often proteinuria in the mother, which can progress to multi-organ dysfunction, including hepatic, renal and cerebral disease, if the fetus and placenta are not delivered. Maternal endothelial dysfunction due to circula…
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Vitamin E in dermatology
Vitamin E is an important fat‑soluble antioxidant and has been in use for more than 50 years in dermatology. It is an important ingredient in many cosmetic products. It protects the skin from various deleterious effects due to solar radiation by acting as a free‑radical scavenger. Experimental studies suggest that vitamin E has antitumorigenic and photoprotective properties. There is a pauc…
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The effect of oral collagen peptide supplementation on skin moisture and the …
Skin dryness and an accelerated fragmentation of the collagen network in the dermis are hallmarks of skin aging. Nutrition is a key factor influencing skin health and consequently its appearance. A wide range of dietary supplements is offered to improve skin health. Collagen peptides are used as a bioactive ingredient in nutricosmetic products and have been shown in preclinical studies to impr…
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Improving Skin Hydration and Age-related Symptoms by Oral Administration of W…
Ceramides are known to play a key role in the skin’s barrier function. An age-dependent decrease in ceramides content correlates with cutaneous clinical signs of dryness, loss of elasticity, and increased roughness. The present placebo-controlled clinical study aims to evaluate if an oral supplementation with glucosylceramides (GluCers) contained in a wheat polar lipids complex (WPLC) was abl…
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Potential Applications of Phyto-Derived Ceramides in Improving Epidermal Barr…
The outer most layer of the skin, the stratum corneum, consists of corneocytes which are coated by a cornified envelope and embedded in a lipid matrix of ordered lamellar structure. It is responsible for the skin barrier function. Ceramides (CERs) are the backbone of the intercellular lipid membranes
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Randomised controlled trial of vitamin E in patients with coronary disease: C…
Vitamin E (&agr;-tocopherol) is thought to have a role in prevention of atherosclerosis, through inhibition of oxidation of low-density lipoprotein. Some epidemiological studies have shown an association between high dietary intake or high serum concentrations of &agr;-tocopherol and lower rates of ischaemic heart disease. We tested the hypothesis that treatment with a high dose of &agr;-tocoph…
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