Oral midazolam is widely used for preoperative sedation in children. We have studied the pharmacokinetics (PK) of both midazolam and its active l-hydroxy metabolite and their contributions to sedative effect in 45 children attending for day surgery.
Adjust dosage according to individual requirements and response, age, body weight, physical and clinical status, underlying pathologic condition(s), type and amount of premedication or concomitant medication, and the nature and duration of the surgical or other procedure; however, individual response also may vary independent of these factors.
In a prospective randomized study efficacy of nasal and sublingual administration of midazolam as premedication in children was evaluated in 60 children aged between 4-10 years with ASA physical status I and II. Patients were divided into two groups of 30 patients each and received midazolam 0.2mgkg-1 either intranasally or sublingually in a randomized manner. Heart rate, oxygen saturation, res…
Proper sedation for neonates undergoing uncomfortable procedures may reduce stress and avoid complications. Midazolam is a shortacting benzodiazepine that is increasingly used in neonatal intensive care units (NICU). However, its effectiveness as a sedative in neonates has not been systematically evaluated
To investigate the adequate infusion dose regimen of midazolam to induce sedation with the Ramsay score 4 with rapid onset during combined spinal and epidural anesthesia
A scalp block is a good perioperative and postoperative anesthesia/rnanalgesia method that has become widespread and preferred by many anesthesiologists.rnMaterial and Method: The present report presented sevenrnpatients, who underwent scalp block due to the evacuation of a subduralrnhematoma. The demographic features of the patients, sedative agents administered,rnand local anesthetic agents a…