Diffusional limitations of mass transport have adverse effects on engineering tissues that normally have high vascularity and cellularity. The current electrospinning method is not always successful to create micropores to encourage cell infiltration within the scaffold, especially when relatively large-sized pores are required. In this study, a slow rotating frame cylinder was developed as th…
Diffusional limitations of mass transport have adverse effects on engineering tissues that normally have high vascularity and cellularity. The current electrospinning method is not always successful to create micropores to encourage cell infiltration within the scaffold, especially when relatively large-sized pores are required. In this study, a slow rotating frame cylinder was developed as th…
After many cranial and spinal neurosurgical removal of meningiomas, reconstruction of the dura mater is needed. The dura has to be meticulously closed following craniotomy (Protasoni et al., 2011), but primary dural closure with sutures alone can be difficult in a loss of native dural tissue (i.e., convexity meningiomas), to enlarge the dural compartment (i.e.,inoperable intramedullary tumors) …
To evaluate the efficacy and safety of non-suture dural closure using a novel dural substitute (GM111) consisting of polyglycolic acid felt with a fibrin-glue-coated area commensurate in size with the dural defect.
Although the treatment of chronic subdural haematoma by burr hole drainage has been performed inrnthe past with or without using a closed drainage system, the problem of intracranial air entrapment stillrnpersists and can cause a deterioration in the level of consciousness or seizures in the postoperative period.rnCerebral infarction may also develop a few days after surgery because of the intr…
Dural defect is a common problem following posterior fossa surgery and needs to be repaired timely so as to prevent the leakage of cerebrospinal fluid (CSF). Currently, there are a few alternatives to human dura mater; however, each has its respective shortcomings such as limited availability, risk of animal pathogens, and poor biocompatibility. To address these issues, we have recently develo…