Patients with epilepsy have a higher risk regarding low quality of life. Objective: to determine the impact of different clinical and demographic factor upon the quality of life. Material and methods: the study group was comprised by 113 patients diagnosed with epilepsy, evaluated between 01.03.2008 and 31.03.2010 in Neurology Clinic from Cluj-Napoca
The objective of this phase 2a study was to assess the activity of PF-06372865, a positive allosteric modulator (PAM) of α2/3/5 subunit-containing GABAA receptors with minimal activity at α1-containing receptors, which are believed to mediate many of the adverse events associated with benzodiazepines, in the epilepsy photosensitivity model as a proof-of-principle of efficacy