Studies in animal models and humans have shown that chlorpyrifos (CPF) causes sensorimotor and cognitive changes. Apart from inhibiting acetylcholinesterase (AChE), the induction of oxidative stress is one of the other molecular mechanisms implicated in OP-evoked toxicity. The present study evaluated the alleviating effect of Phyllanthus niruri, a flavonoid rich plant, on subacute CPF-evoked se…
One of traditional herbs used as medicine in many countries for various uses is the herb Phyllanthus niruri L. Many pre-clinical studies have explored its activities on the immune system. Further pre-clinical studies were done to determine its safety and immunomodulating characteristics on mice and rats. The results of these studies suggested that Phyllanthus niruri L extract is able to modulat…
Penurunan sistem imun pada tuberkulosis paru telah lama diketahui, salah satu keberhasilan dalam penatalaksanaan TB Paru adalah meningkatkan sistem imun penderita dan menggunakan terapi standar yang telah ditetapkan oleh WHO. Ekstrak Phyllanthus niruri telah diketahui dapat meningkatkan sistem imun tubuh. Penelitian ini mencoba untuk mengetahui kadar IFN-g pada pengobatan TB dengan pemberian ek…