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Demographic and Clinical Characteristics of Adult Acute Myeloid Leukemia - Te…
Acute myeloid leukemia (AML) is an acquired clonal frequent malignant disorder of myeloid progenitor cells. Our aim was to study demographical and clinicopathological features of adult Pakistani AML patients at presentation.
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Tobacco Smoke Induces and Alters Immune Responses in the Lung Triggering Infl…
Many studies have been undertaken to reveal how tobacco smoke skews immune responses contributing to the development of chronic obstructive pulmonary disease (COPD) and other lung diseases. Recently, environmental tobacco smoke (ETS) has been linked with asthma and allergic diseases in children. This review presents the most actual knowledge on exact molecular mechanisms responsible for the ske…
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Impacts of cigarette smoking on immune responsiveness: Up and down or upside …
Cigarette smoking is associated with numerous diseases and poses a serious challenge to the current healthcare system worldwide. Smoking impacts both innate and adaptive immunity and plays dual roles in regulating immunity by either exacerbation of pathogenic immune responses or attenuation of defensive immunity. Adaptive immune cells affected by smoking mainly include T helper cells (Th1/Th2/T…
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Usefulness of carcinoembryonic antigen in the diagnosis of small cell lung ca…
Small cell lung cancer (SCLC) includes pure SCLC and SCLC combined with other pathologies (C-SCLC). C-SCLC accounts for about 28% of all SCLCs subjected to surgical resection, but only about 1–3% of C-SCLCs are detected by biopsy. Since less than 5% of SCLC patients are eligible for surgery, it is necessary to develop alternative methods for the detection of C-SCLC
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Small-cell lung cancer (SCLC): ESMO Clinical Practice Guidelines for diagnosi…
An estimated 1.6 million new lung cancers are diagnosed worldwide each year. The highest incidence rates in males are observed in Central/Eastern and Southern Europe (57 and 49 per 100 000, respectively), whereas in women the highest rates are found in Northern Europe (36 per 100 000) . Five-year survival rates of lung cancer patients have only slightly improved during the past decade but rema…
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Diagnostic difficulties with the diagnosis of small cell carcinoma of the lung
Small cell carcinoma of the lung (SCLC) is a well characterized form of lung cancer that is frequently already metastatic at diagnosis. Thus, patients with SCLC are usually treated with chemotherapy, and therefore emphasis has been placed on distinguishing that tumor from squamous cell carcinomas, large cell carcinomas and other pulmonary neoplasms that can more often be managed surgically. SCL…
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