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FOLFOX and FOLFIRI use in Stage IV Colon Cancer: Analysis of SEER-Medicare Data
Shortly after the year 2000, randomized trials demonstrated that patients with metastatic colon cancer treated with infusional 5-fluorouracil (5FU)/leucovorin with either oxaliplatin (FOLFOX) or irinotecan (FOLFIRI) had a comparable progression-free survival benefit versus patients who received 5FU/leucovorin alone. Factors associated with the initial receipt of the FOLFOX or FOLFIRI regimen ar…
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Effects of oxaliplatin-containing adjuvant chemotherapy on short-term surviva…
Oxaliplatin-based adjuvant chemotherapy has been applied as standard treatment for high risk stages II and III colon cancer in many countries. There was no comprehensive report of oxaliplatin use in Indonesia. This research aimed to evaluate the short-term survival of patients with colon cancer treated with such strategy and the prognostic factors.
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Improved Overall Survival With Oxaliplatin, Fluorouracil, and Leucovorin As A…
Three-year disease-free survival (DFS) was significantly improved in patients who had undergone resection with curative intent for stage II or III colon cancer who received bolus plus continuousinfusion fluorouracil plus leucovorin (LV5FU2) with the addition of oxaliplatin (FOLFOX4). Final results of the study, including 6-year overall survival (OS) and 5-year updated DFS, are reported.
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