It is well established that exposure to cigarette smoke (CS), through active smoking and through exposure to secondhand smoke, has immunosuppressive effects, yet how this might affect the microbiome is not known. In this manuscript we focus on the effects of CS on innate host defense response, with particular emphasis on the role of epithelial cells and mucosal immune responses in the nose and …
To compare the effect of two saline nasal sprays on nasal patency and mucociliary clearance in patients with rhinosinusitis.
To evaluate the potential of nasal isotonicrnsaline application to prevent reappearance of cold andrnflu in children during the winter
The European Position Paper on Rhinosinusitis and Nasal Polyps 2012 is the update of similar evidence based position papersrnpublished in 2005 and 2007.rnThe document contains chapters on definitions and classification, we now also propose definitions for ??ifficult to treat??nrhinosinusitis, control of disease and better definitions for rhinosinusitis in children. More emphasis is placed on th…
Saline nasal irrigation (SNI) is often recommended as additional nonpharmacologic treatment, having proven its efficacy in acute and chronicrnrhinosinusitis and for therapy after sinonasal surgery. To date, however, no systematic review or meta-analysis exists showing the influence of SNI on allergicrnrhinitis (AR). This study aimed to establish the impact of SNI on symptoms of AR in different …