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Comparison between the Therapeutic Effect of Metformin, Glimepiride and Their…
To compare the commonly prescribed oral anti-diabetic drug (OAD) combinations to use as an add-on therapy with insulin glargine in patients with uncontrolled type 2 diabetes despite submaximal doses of OADs.
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Efficacy of glimepiride/metformin combination versus glibenclamide/metformin …
The aim of this study was to compare the efficacy of glimepiride/metformin combination versus glibenclamide/metformin for reaching glycemic control in patients with uncontrolled type 2 diabetes mellitus
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Efficacy of glimepiride/metformin fixed-dose combination vs metformin uptitra…
To compare the efficacy and safety of early combination therapy with glimepiride/metformin to metformin uptitration in reducing glycated hemoglobin (HbA1c) levels in Korean type 2 diabetic patients inadequately controlled on low-dose metformin monotherapy.
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Bioequivalence Comparison of Two Formulations of Fixed-Dose Combination Glime…
Glimepiride/metformin (2/500 mg) is an oral antihyperglycemic agent for the treatment of type 2 diabetes. A generic glimepiride/metformin (2/500 mg) fixed-dose combination (FDC) tablet was developed recently. This study was designed to collect data for submission to Korean regulatory authorities to allow the marketing of the test formulation. We evaluated the comparative bioavailability and to…
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An update of genetic basis of PCOS pathogenesis
Polycystic ovary syndrome (PCOS) is a common and complex endocrine disorder that affects 5-20% of reproductive age women. PCOS clinical symptoms include hirsutism, menstrual dysfunction, infertility, obesity and metabolic syndrome. There is a wide heterogeneity in clinical manifestations and metabolic complications.
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PCOS: update and diagnostic approach
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder, commonly diagnosed in reproductive age women. Its estimated prevalence ranges between 5% and 15% [1, 2]. It is often associated with infertility as well as a higher risk of obesity, dyslipidaemia, and detrimental long-term consequences such as type 2 diabetes and cardiovascular disease.
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An update on PCOS in adolescents
Polycystic ovarian syndrome (PCOS) is a common endocrinopathy which can be difficult to treat in adolescents. Fortunately, early identification and treatment can help mitigate some of the metabolic complications. In this review, we reflect on recent literature regarding PCOS diagnosis, associated complications, and treatment options
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Fetomaternal outcome in women with gestational diabetes mellitus
This study was conducted in the department of obstetrics and gynecology GMC Srinagar. Patients with period of gestation more than 28 weeks with Gestational Diabetes Mellitus were included in study group and 100 non-diabetic patients with similar period of gestation were taken as controls. Risk factors and fetomaternal outcome was compared in the two groups
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An update on PCOS in adolescents
Polycystic ovarian syndrome (PCOS) is a common endocrinopathy which can be difficult to treat in adolescents. Fortunately, early identification and treatment can help mitigate some of the metabolic complications. In this review, we reflect on recent literature regarding PCOS diagnosis, associated complications, and treatment options.
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