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Effect of Combined Treatment with MLC601 (NeuroAiDTM) and Rehabilitation on P…
MLC601 has been shown in preclinical studies to enhance neurorestorative mechanisms after stroke. The aim of this post hoc analysis was to assess whether combining MLC601 and rehabilitation has an effect on improving functional outcomes after stroke. Methods: Data from the CHInese Medicine NeuroAiD Efficacy on Stroke (CHIMES) and CHIMES-Extension (CHIMES-E) studies were analyzed. CHIMES-E was …
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The Use of NeuroAiD (MLC601) in Postischemic Stroke Patients
Aim: We aimed to assess the efficacy of MLC601 on functional recovery in patients givenMLC601 after an ischemic stroke. Methods: This is a retrospective cohort study comparing poststroke patients given open-label MLC601 (n = 30; 9 female) for three months and matching patients who did not receive MLC601 from our Stroke Data Bank. Outcome assessed was modified Rankin Scale (mRS) at three mont…
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MLC901 Favors Angiogenesis and Associated Recovery after Ischemic Stroke in Mice
There is increasing evidence that angiogenesis, through new blood vessel formation, results in improved collateral circulation and may impact the long-term recovery of patients. In this study, we first investigated the preventive action of a 5-week pretreatment of MLC901, an herbal extract preparation derived from Chinese medicine, against the deleterious effects of ischemic stroke and its effe…
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