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Found 4 from your keywords: subject="Intranasal Corticoste...
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Intranasal Corticosteroids in Management of Acute Sinusitis: A Systematic Rev…
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Hayward G

Acute sinusitis is a common condition in ambulatory care, where it is frequently treated with antibiotics, despite little evidence of their benefi t. Intranasal corticosteroids might relieve symptoms; however, evidence for this benefi t is currently unclear. We performed a systematic review and meta-analysis of the effects of intranasal corticosteroids on the symptoms of acute sinusitis

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Molecular and clinical pharmacology of intranasal corticosteroids: clinical a…
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Derendorf H

Intranasal corticosteroids (INSs) are effective treatments for allergic rhinitis, rhinosinusitis, and nasal polyposis. In recent years, increased understanding of corticosteroid and glucocorticoid receptor pharmacology has enabled the development of molecules designed specifically to achieve potent, localized activity with minimal risk of systemic exposure. Pharmacologic potency studies using…

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Intranasal corticosteroids for allergic rhinitis: How do different agents com…
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Corren J

Intranasal steroids have proved to be an effective and safe form of therapy for allergic rhinitis. However, as the number of new glucocorticoid compounds has increased over the past decade, it has become important to consider whether significant differences exist between these agents. Pharmacologically, newer drugs such as mometasone furoate and fluticasone propionate appear to have substantia…

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Local and Systemic Safety of Intranasal Corticosteroids
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Sastre J

The safety and effi cacy of intranasal corticosteroids (INCs) are well established for the management of allergic rhinitis, rhinosinusitis, and nasal polyps. As seen in numerous studies, INCs demonstrate markedly reduced systemic bioavailability compared with oral and even inhaled corticosteroids and have shown an excellent safety profi le over 3 decades of use. Nonetheless, concerns remain am…

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