Exforge® (amlodipine/valsartan combination) in hypertension: the evidence of…

This review analyses one of these strategies, which is the development of effective and safe combination therapy. Indeed, at least two antihypertensive agents are often needed to achieve blood pressure control. Exforge® (Novartis) is a new drug combination of the calcium channel blocker, amlodipine, and the angiotensin II receptor blocker, valsartan

Pharmacokinetic and bioequivalence of two formulations of Valsartan/Amlodipin…

Valsartan/amlodipine combination tablets can exert synergistic antihypertensive effects through different mechanisms, significantly lowering blood pressure while also addressing multiple risk factors and comorbidities in patients. This study designed a single-center, randomized, open-label, two-formulations, single-dose, three-cycle, three-sequence, partially repeated crossover controlled trial…

Phase III randomized clinical trial of efficacy and safety of amlodipine and …

Effective antihypertensive therapy is essential for achieving optimal blood pressure (BP) control and reducing cardiovascular events. This double-blind, multicenter, randomized trial aimed to compare the antihypertensive efficacy and safety of a combination of amlodipine (AML) and candesartan cilexetil (CC) versus AML monotherapy in patients with essential hypertension (HTN). After a 4-week run…

2020 International Society of Hypertension Global Hypertension Practice Guide…

The ISH Guidelines Committee extracted evidence-based content presented in recently published extensively reviewed guidelines and tailored and standards of care in a practical format that is easy-to-use particularly in low, but also in high resource settings – by clinicians, but also nurses and community health workers, as appropriate. Although distinction between low and high resource setti…

Medication compliance and clinical outcomes of fixed-dose combinations vs fre…

Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free com‐ binations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medica…

Effect of Amlodipine + Candesartan on Cardiovascular Events in Hypertensive P…

Combination therapy with calcium channel blockers and angiotensin II receptor blockers is recommended as one of the effective therapies for hypertension. However, it remains unclear whether this combination reduces major adverse cardiovascular events (MACEs) in patients with hypertension with coronary artery disease (CAD). The purpose of the present study was to examine the effects of amlod…

Tekanan darah tinggi: mengapa terjadi, bagaimana mengatasinya

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616.132 SMI t

Pendidikan kedokteran berkelanjutan: pengelolaan hipertensi dan gawat darurat…

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616.132 PEN

Myths, misconceptions, and heroics the story of the treatment of hypertension…

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616.132 MOS m

Mencegah serangan jantung dengan menekan kolesterol

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616.132 BAR m