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Autosomal dominant polycystic kidney disease
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease and one of the most common causes of end-stage kidney disease. Multiple clinical manifestations, such as enlarged kidneys filled with growing cysts, hypertension, and multiple extrarenal complications, including liver cysts, intracranial aneurysms, and cardiac valvular disease, show that ADPKD i…
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Joint association of vitamins D and K status with long-term outcomes in stabl…
Kidney transplant recipients (KTRs) experience substantial survival benefit compared with dialysis patients. However, their mortality and graft failure risk remain high. KTRs are often low in micronutrient status, including vitamins D and K. We investigated the association of both vitamins D and K status, and vitamin D treatment with all-cause mortality and death-censored graft failure.
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CLINICAL VALUE OF SCREENING PERITONEAL DIALYSIS PATIENTS FOR BACTERIAL COLONI…
The adoption of the International Society for Peritoneal Dialysis guideline of using mupirocin ointment has been limited by fear of developing mupirocin-resistant organisms. We performed a surveillance program of a large peritoneal dialysis (PD) unit
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Timing of Renal Replacement Therapy for Severe Acute Kidney Injury in Critica…
Acute kidney injury (AKI) affects many intensive care unit patients and is responsible for increased morbidity and mortality. Although life-saving in many situations, renal replacement therapy (RRT) may be associated with complications and the appropriate timing of its initiation is still the subject of intense debate. An early initiation strategy can prevent some metabolic complications where…
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GNAS: A New Nephrogenic Cause of Inappropriate Antidiuresis
Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is the mirror image of nephrogenic diabetes insipidus (NDI): in NDI, the kidneys cannot concentrate the urine, whereas in NSIAD, urinary dilution is impaired, independent of the presence or absence of vasopressin. Consequently, patients with NDI are at risk of hypernatremic dehydration, whereas hyponatremia is a typical manifestation …
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Patient Perspectives on the Meaning and Impact of Fatigue in Hemodialysis: A …
Fatigue is a highly prevalent and debilitating symptom in patients on hemodialysis therapy due to the uremic milieu, the hemodialysis treatment itself, and other comorbid conditions. However, fatigue remains underrecognized and the consequences are underappreciated because it may not be visible in clinical settings. This study aims to describe the experience that patients undergoing maintenance…
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Kidney and hypertension
There is a unique relationship be- the ultimate determinant of BP must be renal handling tween the kidney and blood pressure (BP): on the one hand, of sodium according to this concept. This does not imply rcerenaaslediynsBfuPn,cwtiohnileaonndtphaerotitchuelrarhlaynrde,nhailghdiBsePasaecccealeursaeteasnloinss- that hypertension (HT) is a renal disease, but indicates of function of the disease…
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