Although the number of antihyperglycemic agents has expanded signifcantly, sulfonylureas (in particular gliclazide) remain an important option because of a variety of patient and health system factors. The large, real world, observational, and international EASYDia trial evaluated the efectiveness of gliclazide modifed release (MR) 60 mg in individuals with type 2 diabetes with a broad range …
Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in proposing the best management strategies for an individual patient with a given condition. Guidelines and their recommendations should facilitate decision making of health professionals in their daily practice. However, the final decisions concerning an individual patient must be made by the…
Diabetes mellitus is a risk factor for cardiovascular disease (CVD) and has been associated with 2- to 4-fold higher mortality. Diabetes mellitus–related mortality has not been reassessed in individuals receiving routine care in the United States in the contemporary era of CVD risk reduction
Insulin is the gold standard for treatment of hyperglycemia during pregnancy, when lifestyle measures do not maintain glycemic control during pregnancy. However, recent studies have suggested that certain oral hypoglycemic agents (metformin and glyburide) may be safe and be acceptable alternatives. There are no serious safety concerns with metformin, despite it crossing the placenta.
The objective is to formulate clinical practice guidelines for the treatment of diabetes in older adults.
Hiperglikemia adalah suatu kondisi medik berupa peningkatan kadar glukosa dalam darah melebihi batas normal. Hiperglikemia merupakan salah satu tanda khas penyakit diabetes mellitus (DM), meskipun juga mungkin didapatkan pada beberapa keadaan yang lain. Saat ini penelitian epidemiologi menunjukkan adanya kecenderungan peningkatan angka insidensi dan prevalensi DM tipe-2 di berbagai penjuru du…