Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in proposing the best management strategies for an individual patient with a given condition. Guidelines and their recommendations should facilitate decision making of health professionals in their daily practice. However, the final decisions concerning an individual patient must be made by the…
In approximately 80% of cardiovascular disease-related deaths, patients suffer from coronary atherosclerotic heart disease.Ezetimibe is the first intestinal cholesterol absorption inhibitor.Its combination with statins for treating coronary atherosclerotic heart disease has attracted attention worldwide
The addition of ezetimibe to statin therapy has been reported to result in increased efficacy for reduction of LDL-C levels and achievement of lipid targets, compared with monotherapy
Combination therapy with ezetimibe and statins is recommended in cases of statin in tolerance or insufficiency. The objective of this study wa to compare the efficacy and safety of combination therapy with ezetimibe and rosuvastatin versus those of rosuvastatin monotherapy in patients with hypercholesterolemia