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Adapalene: A Review of its Use in the Treatment of Acne Vulgaris
Adapalene (Differin) is a retinoid agent indicated for the topical treatment of acne vulgaris. In clinical trials, 0.1% adapalene gel has proved to be effective in this indication and was as effective as 0.025% tretinoin gel, 0.1% tretinoin microsphere gel, 0.05% tretinoin cream and 0.1% tazarotene gel once every two days; however, the drug was less effective than once-daily 0.1% tazarotene …
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Adapalene gel 0.3% for the treatment of acne vulgaris: A multicenter, randomi…
Adapalene gel 0.3% was significantly superior to adapalene gel 0.1% and vehicle in success rate, total lesion count, and inflammatory lesion count. A consistent, dose-dependent effect was demonstrated for all efficacy measures. Signs and symptoms were mostly mild to moderate and transient in nature.
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Treatment of Acne Vulgaris
THE MANAGEMENT OF ACNE VULgaris by nondermatologists is increasing.1In this article we attempt to answer the question: what treatments in acne vulgaris have proven efficacy and how are these treatments best administered and individualized to optimize results and minimize complications?Weconsidered the efficacy and safety of topical retinoids, topical antimicrobials, systemic antibiotics, hormon…
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