Gastritis represent a state of inflammation, irritation, or erosion of the stomach lining which may occur suddenly (acute) or gradually (chronic). Generally there is no universally accepted classification of gastritis and early classification was based mainly on the morphology, but recently pathogenic mechanisms have also been incorporated. The gastric mucosa is continuously exposed to many nox…
Prevalence of chronic gastritis has markedly declined in developed populations during the past decades. However, chronic gastritis is still one of the most common serious pandemic infections with such severe killing sequelae as peptic ulcer or gastric cancer. Globally, on average, even more than half of people may have a chronic gastritis at present. Helicobacter pylori infection in childhoo…
Helicobacter pylori (H. pylori ) infection is well known to be associated with the development of precancerous lesions such as chronic atrophic gastritis (AG), or gastric intestinal metaplasia (GIM), and cancer. Various molecular alterations are identified not only in gastric cancer (GC) but also in precancerous lesions. H. pylori treatment seems to improve AG and GIM, but still remains contro…
Gastritis is an inflammation of the stomach lining, which is fairly common and could have different causes. Many kind of agents may lead the stomach into an inflamed statement; in first place, it could be due to non-steroidal anti-inflammatory drugs (NSAID) such as aspirin, ibuprofen, naproxen, etc. (Fig. 1), which are used in different treatments to calm down some specific illness, e.g. rheum…
Two population, intervention, comparison, outcome (PICO) questions were addressed by systematic review: (1) Can therapy for gastroesophageal reflux improve or eliminate cough in adults with chronic and persistently troublesome cough? and (2) Are there minimal clinical criteria to guide practice in determining that chronic cough is likely to respond to therapy for gastroesophageal reflux?
Unlike conventional drinking water, pH 8.8 alkaline water instantly denatures pepsin, rendering it permanently inactive. In addition, it has good acid-buffering capacity. Thus, the consumption of alkaline water may have therapeutic benefits for patients with reflux disease
Laryngopharyngeal reflux (LPR) is a common disorder with protean manifestations in the head and neck. In this retrospective study, we report the efficacy of a wholly dietary approach using alkaline water, a plant-based, Mediterranean-style diet, and standard reflux precautions compared with that of the traditional treatment approach of proton pump inhibition (PPI) and standard reflux precaut…
Intravenous (IV) formulations of proton pump inhibitors are effective for patients in whom oral therapy is not appropriate
Freeze-drying is a method of removing water by sublimation of ice crystals from frozen material. Suitable parameters of process application allow us to obtain best quality products compared to products dried with traditional methods. In pharmaceutical field lyophilization has become important subject to ongoing development and its expansion
It has been demonstrated that therapy with proton pump inhibitors reduces recurrence of bleeding following initial endoscopic treatment of bleeding peptic ulcers