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Phytochemistry and medicinal properties of Phaleria macrocarpa (Scheff.)Boerl…
Phaleria macrocarpa, commonly known as Mahkota dewa is a medicinal plant that is indigenous to Indonesia and Malaysia. Extracts of P. macrocarpa have been used since years in traditional medicine that are evaluated scientifically as well. The extracts are reported for a number of valuable medicinal properties such as anti-cancer, anti-diabetic, anti-hyperlipidemic, anti-inflammatory, anti-bacte…
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Symptomatic treatment of premenstrual syndrome and/or primary dysmenorrhea wi…
DLBS1442, a proprietary and standardized semipolar bioactive extract of the fruit Phaleria macrocarpa, is preclinically proven to have anti-inflmmatory properties. The current clinical study evaluated the effiacy and safety of DLBS1442 in alleviating symptoms of premenstrual syndrome and primary dysmenorrhea
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Antioxidants, Phytochemicals, and Cytotoxicity Studies on P h a l e r i a m a…
In recent years, the utilization of certain medicinal plants as therapeutic agents has drastically increased. Phaleria macrocarpa (Scheff) Boerl is frequently used in traditional medicine. Th present investigation was undertaken with the purpose of developing pharmacopoeial standards for this species. Nutritional values such as ash, fier, protein, fat, and carbohydrate contents were investig…
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Efektivitas DLBS1442 dalam Penanganan Nyeri Endometriosis dan/atau Adenomiosis
DLBS1442 merupakan fraksi bioaktif Phaleria macrocarpa yang memiliki efekmenurunkan ekspresi reseptor estrogen-β (RE-β) dan enzim siklo-oksigenase 2 (COX-2) serta meningkatkan ekspresi gen reseptor progesteron. Ketiga mekanisme tersebut diduga berperan dalam keluhan nyeri pada endometriosis dan atau adenomiosis.
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Endometriosis: advances and controversies in classification, pathogenesis, di…
Endometriosis is an enigmatic disease that could start at birth. Its pathogenesis is supported by different theories. Accumulating facts relate it to a multigenic disorder. In this review of recent publications, the principal symptoms of the disease, pain and infertility, as well as its pathogenesis, diagnosis, and classification will be addressed. Endometriosis presents three main variants: su…
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Endometriosis
Pelvic endometriosis is a complex syndrome characterized by an estrogen-dependent chronic inflammatory process that affects primarily pelvic tissues, including the ovaries. It is caused when shed endometrial tissue travels retrograde into the lower abdominal cavity. Endometriosis is the most common cause of chronic pelvic pain in women and is associated with infertility. The underlying patho…
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The management of menopause in women with a history of endometriosis: a syste…
Endometriosis is typically regarded as a premenopausal disease, resolving after natural or iatrogenic menopause due to declining oestrogen levels. Nonetheless, case reports over the years have highlighted the incidence of recurrent postmenopausal endometriosis. It is now clear that both recurrence and malignant transformation of endometriotic foci can occur in the postmenopausal period. Postm…
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Herbal Medicine for Oligomenorrhea and Amenorrhea: A Systematic Review of Anc…
Menstrual bleeding cessation is one of the most frequent gynecologic disorders among women in reproductive age. The treatment is based on hormone therapy. Due to the increasing request for alternative medicine remedies in the field of women’s diseases, in present study, it was tried to overview medicinal plants used to treat oligomenorrhea and menorrhea according to the pharmaceutical text…
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