DLBS1033 is a bioactive protein fraction isolated from Lumbricus rubellus that tends to be unstable when exposed to the gastrointestinal environment. Accordingly, appropriate pharmaceutical development is needed to maximize absorption of the protein fraction in the gastrointestinal tract. In vitro, ex vivo, and in vivo stability assays were performed to study the stability of the bioactive pro…
DLBS0133 – a lumbrokinase fractionated from the earthworms, Lumbricus rubellus – was a promising agent in patients with ischemic stroke