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Efficacy and safety of etoricoxib 30 mg and celecoxib 200 mg in the treatment…
To compare the efficacy of etoricoxib 30 mg with the generally maximum recommended dose of celecoxib, 200 mg, in the treatment of steoarthritis (OA) in two identically designed studies
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Postoperative Etoricoxib versus Ketoprofen Administration for Pain Management…
This randomized double-blind study compared the analgesic efficacy and tolerability of etoricoxib versus ketoprofen in 165 patients with elective total primary knee arthroplasty
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Cytokine storm in Covid-19-Immunopathological mechanisms, clinical considerat…
Cytokine storm is an acute hyperinflammatory response that may be responsible for critical illness inmany conditions including viral infections, cancer, sepsis, andmulti-organ failure. The phenomenon has been implicated in critically ill patients infected with SARS-CoV-2, the novel coronavirus implicated in COVID-19. Critically ill COVID-19 patients experiencing cytokine storm are believed to …
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Ankylosing spondylitis, chronic fatigue and depression improved after stromal…
Osteoarthritis is a prevalent chronic disease that impacts quality of life and imposes a heavy economic burden. Despite this there is no confirmed treatment that could prevent progressive destruction of osteoarthritic joints. Mesenchymal stem cells with their regenerative and immunosuppressive properties have emerged as a potential therapy
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Exercise programmes for ankylosing spondylitis (Review)
Exercise programmes are oPen recommended for managing ankylosing spondylitis (AS), to reduce pain and improve or maintain functional capacity
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The genetic basis of ankylosing spondylitis: new insights into disease pathog…
Ankylosing spondylitis (AS) is a complex disease involving multiple risk factors, both genetic and environmental. AS patients are predominantly young men, and the disease is characterized by inflammation and ankylosis, mainly at the cartilage–bone interface and enthesis. HLA-B27 has been known to be the major AS-susceptibility gene for more than 40 years. Despite advances made in the past few…
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Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease …
Care models can affect the clinical outcome of patients with rheumatic and musculoskeletal diseases
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Psoriatic Arthritis
Psoriasis is a common skin disease that is associated with multiple coexisting conditions. The most prevalent coexisting condition, psoriatic arthritis, develops in up to 30% of patients with psoriasis and is characterized by diverse clinical features, often resulting in delayed diagnosis and treatment. Initial reports emphasized a benign course in most patients, but it is now recognized that p…
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The Pathogenesis of Rheumatoid Arthritis
Rheumatoid arthritis is a common autoimmune disease that is associated with progressive disability, systemic complications, early death, and socioeconomic costs.1 The cause of rheumatoid arthritis is unknown, and the prognosis is guarded. However, advances in understanding the pathogenesis of the disease have fostered the development of new therapeutics, with improved outcomes. The current trea…
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Knee osteoarthritis: pathophysiology and current treatment modalities
For decades, multiple attempts to fully understand knee osteoarthritis pathophysiology and natural history have been attempted. Despite the extensive amount of research regarding this topic, there are still marked controversies. This multifactorial condition gets influenced by local, systemic, and external factors and its progression and/or response to treatments widely varies from patient to p…
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