The French Society of Anesthesia and Intensive Care Medicine and the French Society of Intensive Care edited guidelines focused on hospital-acquired pneumonia (HAP) in intensive care unit (ICU). The goal of 16 French-speaking experts was to produce a framework enabling an easier decision-making process for intensivists. The guidelines were related to 3 specific areas related to HAP (prevention…
Ceftazidime is a new semisynthetic cephalosporin with marked resistance to ,3-lactamase, a low MIC for gramnegative bacilli, and a broad antimicrobial spectrum against Haemophilus influenzae, Enterobacter cloacae, Citrobacter freundii, Serratia marcescens, indole-positive Proteus spp., and Pseudomonas aeruginosa
It has been suggested that the antibiotic-induced release of lipopolysaccharide (LPS) is an important cause of the development of septic shock in patients treated for severe infections caused by gram-negative bacteria. b-Lactam antibiotics change the integrity of the bacterial cell envelope by binding to penicillin-binding proteins (PBP) in the membrane and thus may affect the amount of LPS …
TYPHOID fever is a systemic infection with the bacterium Salmonella enterica serotype typhi. This highly adapted, human-specific pathogen has evolved remarkable mechanisms for persistence in its host that help to ensure its survival and transmission.