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Salt and cardiovascular disease: insufficient evidence to recommend low sodiu…
Several blood pressure guidelines recommend low sodium intake (
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Standards of practice in acute ischemic stroke intervention: International re…
After the five positive randomized controlled trials showing the benefit of mechanical thrombectomy (MT) in the management of acute ischemic stroke (AIS) with emergent large vessel occlusion (ELVO), a multisociety meeting was organized during the 16th Congress of the World Federation of Interventional and Therapeutic Neuroradiology (WFITN), October 2015, Gold Coast, Australia. This meeting was…
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Acute Stroke Intervention A Systematic Review
Acute ischemic stroke is a major cause of mortality and morbidity in the United States.We review the latest data and evidence supporting catheter-directed treatment for proximal artery occlusion as an adjunct to intravenous thrombolysis in patients with acute stroke.
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Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTER…
There is much uncertainty about the eff ects of early lowering of elevated blood pressure (BP) after acute intracerebral haemorrhage (ICH). Our aim was to assess the safety and effi ciency of this treatment, as a run-in phase to a larger trial.
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The safety of antithrombotic therapy in patients with cerebral microbleeds an…
The impact of cerebral microbleeds on the safety of antithrombotic therapy has recently received considerable attention. We investigated the safety of antithrombotic therapy in patients with cerebral microbleeds and cardiogenic cerebral embolism caused by nonvalvular atrial fibrillation
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Management of blood pressure in heart failure
Hypertension is a common comorbidity in patients with heart failure and most drugs that have demonstrated to improve prognosis in this population have the potential to reduce blood pressure. Nonetheless, the relationship between blood pressure and clinical outcomes and the relevance of blood pressure reduction in heart failure remains unclear.
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Premature Ventricular Contraction–Induced Cardiomyopathy
Premature ventricular contractions are of common occurrence in routine clinical practice. Though generally perceived as of benign consequence in healthy people in the absence of heart disease, their presence can be a harbinger of fatal ventricular tachyarrhythmia in individuals with structural heart disease. With some of the latest insights into the treatment of ventricular tachyarrhythmia, esp…
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Cardiac characteristics in the premature ventricular contraction patients wit…
Background/Aims: Frequent (sustained) premature ventricular contractions (PVCs) lead to ventricular tachycardia (VT), which triggers ventricular fibrillation and sudden cardiac death. The cardiac characteristics and risk prediction in frequent/sustained PVC patients with or without VT have been still in need of investigation. Methods: The data from patients with frequent PVCs via 24 h ambulator…
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Nephrotic syndrome in children
Nephrotic syndrome is an important chronic disease in children, characterized by minimal change disease in the majority. Research on pathogenesis has emphasized the importance of T lymphocyte dysregulation and vascular permeability factors that might alter podocyte function and permselectivity. While mutations in genes that encode important podocyte proteins have also been identified, a hypoth…
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Nephrotic Syndrome
Nephrotic syndrome is a disorder of the kidneys that results from increased permeability of the glomerular filtration barrier. It is characterized by 4 major clinical characteristics that are used in establishing the diagnosis: proteinuria, hypoalbuminemia, edema, and hyperlipidemia. This article reviews nephrotic syndrome in the pediatric population, with special attention paid to minimal chan…
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