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Electrospun Fibrous Mats with High Porosity as Potential Scaffolds for Skin T…
Diffusional limitations of mass transport have adverse effects on engineering tissues that normally have high vascularity and cellularity. The current electrospinning method is not always successful to create micropores to encourage cell infiltration within the scaffold, especially when relatively large-sized pores are required. In this study, a slow rotating frame cylinder was developed as th…
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Electrospun Fibrous Mats with High Porosity as Potential Scaffolds for Skin T…
Diffusional limitations of mass transport have adverse effects on engineering tissues that normally have high vascularity and cellularity. The current electrospinning method is not always successful to create micropores to encourage cell infiltration within the scaffold, especially when relatively large-sized pores are required. In this study, a slow rotating frame cylinder was developed as th…
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Dural Reconstruction in Meningioma Surgery
After many cranial and spinal neurosurgical removal of meningiomas, reconstruction of the dura mater is needed. The dura has to be meticulously closed following craniotomy (Protasoni et al., 2011), but primary dural closure with sutures alone can be difficult in a loss of native dural tissue (i.e., convexity meningiomas), to enlarge the dural compartment (i.e.,inoperable intramedullary tumors) …
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Knowledge Sharing Session : Let's Play with Verb
Berbicara dalam bahasa Inggris sering menjadi tantangan. Acapkali, kita kesulitan untuk membentuk kalimat yang utuh dan rapi. Belajar tata bahasa (Grammar) dapat menjadi dalam satu cara untuk belajar menyusun kalimat yang baik dan lancar berbahasa Inggris. Namun, kata kerja (verb) sering tidak diperhatikan, padahal ada banyak sekali cara menggunakan kata kerja yang dapat memperkaya kalimat kita…
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Hyperuricemia, A new cardiovascular risk
Hyperuricemia is strongly linked to increased cardiovascular risk, including hypertension, coronary artery disease, arrythmia, and heart failure. Uric acid, as the end-product of purine metabolism, plays a critical role in cellular processes, but elevated levels can drive inflammation and oxidative stress. This review aims to emphasize the robust association between hyperuricemia and cardiovasc…
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Standardized bioactive fraction of Phaleria macrocarpa (Proliverenol) prevent…
The data support our hypothesis that Proliverenol has a potential ability in protecting cells from ethanol-induced hepatotoxicity. We propose that Proliverenol provides hepatoprotective activity through up-regulating expression of APEX1 that repress DNA fragmentation, and down-regulating expression of nuclear factor-kB, tumor necrosis factora and caspase-8, which therefore repress ALT leakage a…
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Fraksi Bioaktif dan Inovasi Terapeutik: Jembatan Etnofarmasi dan Sains Modern
Studi fraksi bioaktif telah muncul sebagai bidang transformatif dalam farmakologi modern, menekankan pemurnian dan isolasi senyawa yang dipandu bioassay dengan potensi terapeutik.1,2,3 Makalah ini mengeksplorasi mekanisme, metodologi, dan implikasi fraksi bioaktif dalam memajukan penemuan obat. Mengambil pengetahuan etnofarmakologi, makalah ini menyoroti integrasi k…
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The Effect of Phaleria macrocarpa Bioactive Fraction (Proliverenol) Supplemen…
Liver is considered one of the most vital organs, acting as the center of metabolism of nutrients and excretion of waste products. Non-alcoholic fatty liver disease (NAFLD) is one of the main causes of chronic liver disease. The management of NAFLD continues to evolve, and clinicians are currently faced with a variety of alternative options, both non-pharmac…
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Comparative nasal airflow with loratadine-pseudoephedrine and fluticasone nas…
Although it is known that oral antihistamine-pseudoephedrine combination tablets have a faster onset than intranasal corticosteroid sprays in the treatment of allergic rhinitis after the first dose, the magnitude of change has not been measured in a comparative manner. Furthermore, the sensation of sprayed liquid in the nose may lead patients to mistakenly believe that intranasal steroid sprays…
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Montelukast Use and the Risk of Neuropsychiatric Adverse Events in Children
In this large study of children and adolescents based on data from routine clinical practice, there was no association between use of montelukast and the risk of neuropsychiatric adverse events. In aggregation with other robust observational studies, these results can inform the management of asthma and allergic rhinitis in this patient group.
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