S-index and APRI Score to Predict Liver Fibrosis Chronic in Hepatitis B and C…

A great interest has been dedicated to the development of non invasive predictive models in recent years to substitute liver biopsy for fibrosis assessment and follow-up. The aim of this study was to compare the accuracy between S-index and aspartate aminotransferase to platelet ratio index (APRI) to FibroScan for predicting liver fibrosis in chronic hepatitis B and C patients

The role of tumour necrosis factor in hepatitis B infection: Jekyll and Hyde

Chronic hepatitis B (CHB) is a major health problem worldwide and is associated with significant long-term morbidity and mortality. The hepatitis B virus (HBV) is a hepatotropic virus that is capable of integrating in the host nucleus permanently resulting in lifelong infection. To date, there is no definitive cure for HBV, as our current treatments cannot eradicate the viral reservoir that ha…

Impact of age on the diagnostic performances and cut-offs of APRI and FIB-4 f…

The APRI AUROC in patients aged

AST to platelet ratio index (APRI) for the noninvasive evaluation of liver fi…

Liver biopsy is the recognized gold standard for liver fibrosis staging. The aspartate minotransferase to platelet ratio index (APRI) has been proposed as a noninvasive and readily available tool for the assessment of liver fibrosis in chronic hepatitis C (CHC). This study aimed to validate, in a Mexican tertiary health care setting, the diagnostic usefulness of APRI in CHC, nonalcoholic fatty…

Variceal bleeding in cirrhotic patients

Variceal bleeding is one of the major causes of death in cirrhotic patients. The management during the acute phase and the secondary prophylaxis is well defined. Recent recommendations (2015 Baveno VI expert consensus) are available and should be followed for an optimal management, which must be performed as an emergency in a liver or general intensive-care unit. It is based on the early admini…

Patient Diagnosis Resource for Radiation Colitis

Your doctor has determined that you have radiation colitis, an inflammation of the colon that occurs as a side effect of cancer radiation therapy to the abdomen or pelvis. The condition can arise from external radiation treatment delivered by a high energy X-ray machine or internal radiation therapy, which is delivered through small implants placed directly into or near the cancerous tumor

Idiopathic Noncirrhotic Portal Hypertension

Cirrhosis is the most common cause of portal hypertension but a heterogeneous group of clinical entities, collectively referred to as non-cirrhotic portal hypertension (NCPH), can also lead to elevation of the portal venous pressure in the absence of cirrhosis. Common causes of NCPH are nonalcoholic or alcoholic steatohepatitis, primary biliary cholangitis, primary sclerosing cholangitis, conge…

BOOK REVIEW : Disease-related Malnutrition: An Evidence-based Approach to Tre…

Whoever cares for cost–benefit and cost–effectiveness of treatments must use this book; its focus is to establish, share with the readers and entice them to practice, adequate evidence-base for the provision of nutritional therapy

Macroalgal Fucoidan extracts: a new opportunity for marine cosmetics

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Effect of Fucoidan on the Biotinidase Kinetics in Human Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is difficult to treat with anticancer drugs. Therefore, development of new drugs for HCC is required.