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The Efficacy of Oral Etoricoxib in Pain Control During Colposcopy-Directed Ce…
Objective: To investigate the effectiveness and safety of oral etoricoxib administration before colposcopic procedure for pain relief during and after colposcopy. Methods: A prospective double-blind, randomized controlled trial was conducted at the colposcopy unit of Thammasat University Hospital, Thailand from August 2022 to January 2023. The participants were women undergoing colposcopy. …
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Comparing pre‑ and postoperative etoricoxib administration versus only post…
Objectives: This study aimed to compare the impact of pre- and postoperative etoricoxib administration versus only postoperative on third molar extraction sequelae and oral health quality of life. Materials and methods: This prospective quasi experimental study involved 56 patients, divided into a study group receiving preemptive etoricoxib 120 mg before surgery and postoperative etoricoxib…
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Nationwide Etoricoxib Injection Clinical Experience (NICE): Real-World Eviden…
Pain is a major health issue globally. Etoricoxib, a highly selective COX-2 inhibitor, given orally, has been found to be efficacious and safe in the management of acute and chronic pain. Oral etoricoxib has been extensively studied; however, there is a lack of research exploring the use of etoricoxib via alternative routes, specifically intramuscular (IM) injection. This study aimed to evaluat…
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Electrospun Fibrous Mats with High Porosity as Potential Scaffolds for Skin T…
Diffusional limitations of mass transport have adverse effects on engineering tissues that normally have high vascularity and cellularity. The current electrospinning method is not always successful to create micropores to encourage cell infiltration within the scaffold, especially when relatively large-sized pores are required. In this study, a slow rotating frame cylinder was developed as th…
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Electrospun Fibrous Mats with High Porosity as Potential Scaffolds for Skin T…
Diffusional limitations of mass transport have adverse effects on engineering tissues that normally have high vascularity and cellularity. The current electrospinning method is not always successful to create micropores to encourage cell infiltration within the scaffold, especially when relatively large-sized pores are required. In this study, a slow rotating frame cylinder was developed as th…
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Dural Reconstruction in Meningioma Surgery
After many cranial and spinal neurosurgical removal of meningiomas, reconstruction of the dura mater is needed. The dura has to be meticulously closed following craniotomy (Protasoni et al., 2011), but primary dural closure with sutures alone can be difficult in a loss of native dural tissue (i.e., convexity meningiomas), to enlarge the dural compartment (i.e.,inoperable intramedullary tumors) …
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Knowledge Sharing Session : Let's Play with Verb
Berbicara dalam bahasa Inggris sering menjadi tantangan. Acapkali, kita kesulitan untuk membentuk kalimat yang utuh dan rapi. Belajar tata bahasa (Grammar) dapat menjadi dalam satu cara untuk belajar menyusun kalimat yang baik dan lancar berbahasa Inggris. Namun, kata kerja (verb) sering tidak diperhatikan, padahal ada banyak sekali cara menggunakan kata kerja yang dapat memperkaya kalimat kita…
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Hyperuricemia, A new cardiovascular risk
Hyperuricemia is strongly linked to increased cardiovascular risk, including hypertension, coronary artery disease, arrythmia, and heart failure. Uric acid, as the end-product of purine metabolism, plays a critical role in cellular processes, but elevated levels can drive inflammation and oxidative stress. This review aims to emphasize the robust association between hyperuricemia and cardiovasc…
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Standardized bioactive fraction of Phaleria macrocarpa (Proliverenol) prevent…
The data support our hypothesis that Proliverenol has a potential ability in protecting cells from ethanol-induced hepatotoxicity. We propose that Proliverenol provides hepatoprotective activity through up-regulating expression of APEX1 that repress DNA fragmentation, and down-regulating expression of nuclear factor-kB, tumor necrosis factora and caspase-8, which therefore repress ALT leakage a…
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Fraksi Bioaktif dan Inovasi Terapeutik: Jembatan Etnofarmasi dan Sains Modern
Studi fraksi bioaktif telah muncul sebagai bidang transformatif dalam farmakologi modern, menekankan pemurnian dan isolasi senyawa yang dipandu bioassay dengan potensi terapeutik.1,2,3 Makalah ini mengeksplorasi mekanisme, metodologi, dan implikasi fraksi bioaktif dalam memajukan penemuan obat. Mengambil pengetahuan etnofarmakologi, makalah ini menyoroti integrasi k…
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