Parameters for starting antibiotic therapy such as CRP andleukocytosis are considered non-specific. Previous studies have shown the Neutrophil-Lymphocyte Count Ratio (NLCR) can serve as the basis of bacterial infection, the level of infection, and the basis of antibiotic therapy. Compared with the Procalcitonin parameter, this NLCR is rapid, an inexpensive and requires no additional sampling
Aspiration pneumonia and pneumonitis are part of the pneumonia continuum and share similarities in pathophysiology, microbiology, and treatment. Modern microbiology demonstrates that the lung is not sterile, and isolates in aspiration pneumonia frequently include aerobes or mixed cultures. Treatment for aspiration pneumonia should include antibiotic coverage for oral anaerobes, aerobes associat…
Escherichia coli adalah bakteri fakultatif anaerob, berbentuk batang, bersifat gram negatif, dan merupakan flora normal intestinal. E. coli juga merupakan bakteri yang paling sering menyebabkan infeksi saluran kemih dan infeksi nosokomial. Resistensi E. coli terhadap berbagai antibiotika telah banyak dilaporkan, khususnya antibiotika golongan β-laktam. Tujuan penelitian ini adalah untuk mengis…
To describe overall site-specific Hospital acquired infections (HAI) rates, and to describe the microbiological and antibiotic resistance profiles of infecting pathogens, together with their impact on multidrug-resistant bacteria-associated mortality.
Rumah sakit sebagai tempat perawatan dan penyembuhan pasien, ternyata rentan terjadinya infeksi penyakit, begitu pula yang terjadi di RSPI Prof. Dr. Sulianti Saroso. Oleh karena itu, perlu adanya penelitian jumlah dan jenis kuman di lingkungan RSPI-SS. Penelitian ini merupakan penelitian observasional dengan pendekatan cross selection. Jenis kuman yang akan diteliti adalah kuman yang terdapat p…
Intensive care unit (ICU)-acquired infections are a challenging health problem worldwide, especially when caused by multidrug-resistant (MDR) pathogens. In ICUs, inanimate surfaces and equipment (e.g., bedrails, stethoscopes, medical charts, ultrasound machine) may be co taminated by bacteria, including MDR isolates. Cross-transmission of microorganisms from inanimate surfaces may have a sign…
Management of health-care waste is an integral part of hospital hygiene and infection control. Health-care waste should be considered as a reservoir of pathogenic microorganisms, which can cause contamination and give rise to infection. If waste is inadequately managed, these microorganisms can be transmitted by direct contact, in the air, or by a variety of vectors.
The rate of nosocomial infection appears to depend on whether it is calculated using the Center for Disease Control (CDC) or carrier state criteria. The objective of this study was to differentiate between primary endogenous (PE), secondary endogenous (SE) and exogenous (EX) infections, and to compare this classification with CDC criteria for nosocomial infections.
The discovery of penicillin by Fleming led to tremendous benefits in clinical medicine. Penicillin quickly became one of the most commonly prescribed drugs in the world. Despite a wide therapeutic index, it soon became clear that the penicillins could produce a vast array of immunological responses that could cause severe and fatal allergic reactions in some patients
Drug allergy to antibiotics may occur in the form of immediate or non-immediate (delayed) hypersensitivity reactions. Immediate reactions are usual-ly IgE-mediated whereas non-immediate hypersensitivity reactions are usually non-IgE or T-cell mediated. The clinical manifestations of antibiotic allergy may be cutaneous, organ-specific (e.g., blood dyscracias, hepatitis, interstitial nephritis), …