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Osteoporosis: A Review
Osteoporosis is a progressive systemic skeletal disease characterizedby reduced bone mass/density and microarchitectural deterioration of bone tissue. It is a “silent disease” as there are no symptoms prior to a fracture.The prevalence of osteoporosis increases markedly with age.DEXA is regarded as the gold standard technique for diagnosis of osteoporosis
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Menopausal hormone therapy 2019
As women transition through the menopause, the decreased production of estrogens can manifest itself in three different ways: - Immediate vasomotor, sleep and emotional impacts - Later local genital tract and urinary symptoms - Long-term cardiovascular, skeletal and other ‘chronic’ consequences
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Update on Safety Profiles of Vitamins B1, B6, and B12: A Narrative Review
The neurotropic B vitamins B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) are essential for proper functioning of the nervous system. Deficiencies may induce neurological disorders like peripheral neuropathy (PN) and mainly occur in vulnerable populations (eg, elderly, diabetics, alcoholics). As epidemiologic cohort studies raised safety concerns about vitamin B6/B12 intake being potentia…
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Vitamin
Vitamin, any of several organic substances that are necessary in small quantities for normal health and growth in higher forms of animal life. Vitamins are distinct in several ways from other biologically important compounds such as proteins, carbohydrates, and lipids. Although these latter substances also are indispensable for proper bodily functions, almost all of them can be synthesized by a…
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The Nutritional Management of Hepatic Encephalopathy in Patients with Cirrhos…
The assessment of nutritional status in patients with cirrhosis is problematic. In addition there are significant sex-related differences in body composition and in the characteristics of tissue loss which limit the usefulness of techniques based on measures of muscle mass and function in women. Techniques which combine subjective and objective variables provide reasonably accurate information…
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Vitamin E in dermatology
Vitamin E is an important fat‑soluble antioxidant and has been in use for more than 50 years in dermatology. It is an important ingredient in many cosmetic products. It protects the skin from various deleterious effects due to solar radiation by acting as a free‑radical scavenger. Experimental studies suggest that vitamin E has antitumorigenic and photoprotective properties. There is a pauc…
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High-Dose Cholecalciferol Booster Therapy is Associated with a Reduced Risk o…
The worldwide pandemic of 2019 novel coronavirus disease (COVID-19) has posed the most substantial and severe public health issue for several generations, and therapeutic options have not yet been optimised. Vitamin D (in its “parent” form, cholecalciferol) has been proposed in the pharmacological management of COVID-19 by various sources. We aimed to determine whether COVID-19 mortality wa…
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Effectiveness of In-Hospital Cholecalciferol Use on Clinical Outcomes in Como…
Little information is available on the beneficial effects of cholecalciferol treatment in comorbid patients hospitalized for COVID-19. The aim of this study was to retrospectively examine the clinical outcome of patients receiving in-hospital high-dose bolus cholecalciferol. Patients with a positive diagnosis of SARS-CoV-2 and overt COVID-19, hospitalized from 15 March to 20 April 2020, were co…
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Association of Vitamin D Status and Other Clinical Characteristics With COVID…
Vitamin D treatment has been found to decrease the incidence of viral respiratory tract infection, especially in patients with vitamin D deficiency. Whether vitamin D is associated with coronavirus disease 2019 (COVID-19) incidence is unknown
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Vitamin D-Mediated Regulation of Intestinal Calcium Absorption
Vitamin D is a critical regulator of calcium and bone homeostasis. While vitamin D has multiple effects on bone and calcium metabolism, the regulation of intestinal calcium (Ca) absorption efficiency is a critical function for vitamin D. This is necessary for optimal bone mineralization during growth, the protection of bone in adults, and the prevention of osteoporosis. Intestinal Ca absorption…
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