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Informed Consent in Pediatric Research
Pediatric drug research is gradually becoming more and more accepted as the norm for assessing whether a drug is safe and efficacious for infants and children. The process of informed consent and assent for these trials presents a major challenge. The aim of this review is to map historical, ethical and legal aspects relevant to the challenges of informed consent in the setting of pediatric dru…
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“Honk Against Homophobia”: Rethinking Relations Between Media and Sexual …
The theory of “symbolic annihilation” or “symbolic violence” has been used in academic literature to describe the way in which sexual minorities have been ignored, trivialized, or condemned by the media. This article aims to de-center research from issues of media representation to consider the capacity for minority groups to proactively use new media and its various avenues for interac…
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Neurocognitive Treatments for Eating Disorders and Obesity
Neurocognitive treatments are emerging and show initial promise for eating and weight disorders. Further research is necessary to determine whether these treatments can be used as stand-alone treatments or whether they need to be used as an adjunct to or in conjunction with other evidence-based treatments to improve outcomes.
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HLA antigens in individuals with down syndrome and alopecia areata
Seventy per cent of evaluated individuals in the DS and AA group were male; presented mean age of 18.6 (SD ± 7.2) years and 70% were Caucasian. We observed involvement of the scalp, with a single lesion in 10% and multiple in 90% of subjects. It was observed that there is no significant difference in the frequency distributions of the alleles HLA loci A, B, C, DRB1 and DQB1 of subjects studie…
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Clinical Characteristics of Alopecia Areata in Down Syndrome
This study was undertaken to better understand clinical characteristics, environmental and physical events in Down syndrome (DS) and alopecia areata (AA). This cross-sectional study included 18 DS patients who were currently presenting or had presented AA. We evaluated gender, age, location and type of AA, presence of autoimmune disease or atopy, AA in first-degree relatives, and environmental,…
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Obstetric hemorrhage in a case of hypertrophic obstructive cardiomyopathy wit…
The physiological changes occurring during pregnancy and labor may reveal or exacerbate the symptoms of hypertrophic obstructive cardiomyopathy (HOCM). The addition of obstetric hemorrhage to this presents a unique challenge to the anesthesiologists and intensivists managing these patients in the operation theatres and the Intensive Care Units. Here we present a case of HOCM with automatic impl…
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Alopecia Areata and Down Syndrome: A True Association or a Coincidence
The cause of alopecia areata (AA) is not entirely understood, although a strong genetic basis for this condition has been suggested.[1] Several studies have showed that AA is associated with Down syndrome (DS), implicating that a causative gene for this condition is located on chromosome 21
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Hubungan Perilaku Merokok dengan Gambaran Faal Paru pada Jemaah Haji
Banyaknya jemaah haji Indonesia memiliki kebiasaan merokok. Kebiasaan merokok tersebut bisa menyebabkan gangguan faal paru. Gangguan faal paru tersebut bisa bersifat obstruktif, restriktif, dan campuran. Banyak studi sebelumnya menunjukkan hubungan kuat antara kebiasaan merokok dengan penyakit saluran napas
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EFEK PERILAKU MEROKOK TERHADAP SALURAN PERNAPASAN
Perilaku merokok adalah menghisap tembakau yang dibakar kedalam tubuh melalui saluran pernapasan dan menghembuskannya keluar, termasuk rokok kretek, rokok putih, atau bentuk lainnya yang asapnya mengandung susunan senyawa gas dan partikel seperti karbon dioksida, air, karbon monoksida, partikular (kebanyakan tar), nikotin, nirtogen oksida, hidrogen sianida, amoniak, formaldehida, fenol dan pulu…
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Practical Genetics : Tuberous sclerosis
Tuberous sclerosis is a serious inherited disease which poses major challenges for affected families and those caring for them. Identification of the genes causing the condition and study of their protein products has shed light on the pathogenesis of the disease and provided valuable new information about signalling pathways regulating protein synthesis and cell growth. There is now the exciti…
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