Filter by
Anticoagulants: A Review of the Pharmacology, Dosing, and Complications
Anticoagulants remain the primary strategy for the prevention and treatment of thrombosis. Unfractionated heparin, low molecular weight heparin, fondaparinux, and warfarin have been studied and employed extensively with direct thrombin inhibitors typically reserved for patients with complications or those requiring intervention. Novel oral anticoagulants have emerged from clinical development a…
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Bioavailability of fondaparinux to critically ill patients
Venous thromboembolism is a common problem in the intensive care unit (ICU). To decrease its incidence, prophylactic pharmacologic interventions are part of the ICU routine. However, common ICU conditions may impair the bioavailability of subcutaneously administered agents. The present study evaluates the bioavailability of prophylactic subcutaneous fondaparinux to critically ill patients
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
THE ANTIPHOSPHOLIPID SYNDROME
The first antiphospholipid antibody, a complementfixing antibody that reacted with extracts from bovine hearts, was detected in patients with syphilis in 1906. The relevant antigen was later identified as cardiolipin, a mitochondrial phospholipid. This observation became the basis for the Venereal Disease Research Laboratory (VDRL) test for syphilis that is currently used. Mass screening of bl…
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Fondaparinux: A Pharmacoeconomic Review of its Use in the Management of Non-…
In OASIS-5, a large pivotal trial in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS), subcutaneous fondaparinux 2.5 mg once daily was noninferior to subcutaneous enoxaparin 1mg/kg twice daily (both agents were administered over a mean of about 5 days in combination with antiplatelet therapy) in reducing death or ischaemic events at 9 days, and the efficacy was maintain…
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Use of fondaparinux in a patient with antiphospholipid antibody syndrome and …
The diagnosis of antiphospholipid antibody syndrome (APS) requires one or more vascular thromboses in a patient with antiphospholipid antibodies or lupus anticoagulants detected in the blood on at least two occasions 6 weeks apart
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Efficacy and safety of fondaparinux for the prevention of venous thromboembol…
To determine the efficacy and safety of the anticoagulant fondaparinux in older acute medical inpatients at moderate to high risk of venous thromboembolism
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Pharmacology of anticoagulants used in the treatment of venous thromboembolism
Anticoagulant drugs are the foundation of therapy for patients with VTE. While effective therapeutic agents, anticoagulants can also result in hemorrhage and other side effects. Thus, anticoagulant therapy selection should be guided by the risks, benefits and pharmacologic characteristics of each agent for each patient. Safe use of anticoagulants requires not only an in-depth knowledge of thei…
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Diagnosis dan Tatalaksana Deep Vein Thrombosis
Deep vein thrombosis (DVT) adalah bekuan darah di vena dalam yang sebagian besar tersusun atas fibrin, sel darah merah, serta sebagian kecil komponen leukosit dan trombosit. Diagnosis DVT ditegakkan berdasarkan gejala klinis dan pemeriksaan penunjang berupa laboratorium dan radiologi. Penatalaksanaan DVT dapat berupa terapi non-farmakologis, farmakologis, ataupun pembedahan
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Fondaparinux Sodium Compared With Low-Molecular-Weight Heparins for Periopera…
Fondaparinux sodium has been compared with low-molecular-weight heparins (LMWH) in randomized controlled trials for perioperative surgical thromboprophylaxis. However, the results from these studies are inconsistent in terms of efficacy and safety to reach a clinical decision. The objective of this study was to systematically review the randomized controlled trials comparing the efficacy and sa…
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Fondaparinux or Enoxaparin for the Initial Treatment of Symptomatic Deep Veno…
The current standard initial therapies for deep venous thrombosis are low-molecular-weight heparin and unfractionated heparin. In a dose-ranging study of patients with symptomatic deep venous thrombosis, fondaparinux had efficacy and a safety profile similar to those of low-molecular-weight heparin (dalteparin)
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- -
Computer Science, Information & General Works 
Philosophy & Psychology 
Religion 
Social Sciences 
Language 
Pure Science 
Applied Sciences 
Art & Recreation 
Literature 
History & Geography