The choice of drug used to facilitate endotracheal intubation in trauma patients during rapid sequence induction (RSI) may have an impact on survival. Ketamine is commonly used in the hemodynamically unstable trauma patient although it has been associated with side effects. This review sought to investigate whether ketamine should be preferred over other induction agents for RSI in trauma pati…
Diabetes during pregnancy can be classified as gestational diabetes mellitus (GDM) or pre-existing diabetes. Many women identified as having diabetes mellitus for the first time in pregnancy are classified as having GDM, although they may actually have pre-existing diabetes. This diagnosis has significant implications for obstetric anaesthesia with regards to maternal and fetal outcomes.
With interest, we read the review “Role of paced breathing for treatment of hypertension” [1]. Several types of interventions were described; the main focus of the paper was on a commercially available paced breathing device called the RESPeRATE. We have concerns with the current review, which is remarkably comparable to a previous, criticized, non-systematic review by the same authors [2,…
BMT from MRD/1MMRD is the treatment of choice. When a MRD/1MMRD is not available, upfront BMT from a MUD should be considered for patients with only a slim chance of responding to IST. UCBT and haploidentical HSCT are promising options. This updated treatment algorithm should improve overall outcomes for children with AA.
The guideline group was selected to be representative of UK-based aplastic anaemia (AA) medical experts. Recommendations are based on review of the literature using MEDLINE and PUBMED up to December 2014 under the heading: ‘aplastic anemia’.
Technological advancements in imaging and intervention have allowed many disease processes to be treated outside of the operating room (OR). These advancements have provided alternative treatments to patients who are considered too high a risk or too unstable for traditional surgical procedures. As a result, there has been considerable increase in use of various levels of procedural sedation, i…
Appropriate supervision has been shown to reduce medical errors in anesthesiology residents and other trainees across various specialties. Nonetheless, supervision of pediatric anesthesiology fellows has yet to be evaluated. The main objective of this survey investigation was to evaluate supervision of pediatric anesthesiology fellows in the United States. We hypothesized that there was an in…
Procedural sedation and analgesia (PSA) has become a widespread practice given the increasing demand to relieve anxiety, discomfort and pain during invasive diagnostic and therapeutic procedures. The role of, and credentialing required by, anaesthesiologists and practitioners performing PSA has been debated for years in different guidelines. For this reason, the European Society of Anaesthesiol…
Cancer is now overtaking cardiac disease as the most common cause of death in Western societies. Perhaps the main reason for this is increased life expectancy at birth. However, elsewhere, cancer is also rising in incidence, due in no small part to chronic infections such as viral hepatitis. Given improved survival with aggressive and modern treatments, surgery is becoming more important in the…
Surgery is an important component of treatment in cancer patients. However, surgical stress, anesthesia, and perioperative analgesia interfere with the host immune defense mechanisms and may contribute to metastatic dissemination of malignant tumors and cancer progression. Little is known about the effects of anesthesia on tumor recurrence. In vivo studies and clinical data show some evidence t…