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Laryngeal framework surgery: current strategies
Laryngeal framework surgery (LFS) is an indispensable surgical approach for the treatment of voice problems. The purpose of this review is to single out some relevant articles published on the topic of LFS from 2015 to mid-2016. Articles referring to injection laryngoplasty (augmentation) are entirely left aside
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Pharmacological Treatment of Diabetic Neuropathic Pain
Neuropathic pain continues to be a difficult and challenging clinical issue to deal with effectively. Painful diabetic polyneuropathy is a complex pain condition that occurs with reasonable frequency in the population and it maybe extremely difficult for clinicians to provide patients with effective analgesia. Chronic neuropathic pain may occur in approximately one of every four diabetic patie…
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PREFILLED SYRINGES: INNOVATIONS THAT MEET THE GROWING DEMAND
The use of prefilled syringes is a modern way to apply parenteral drugs. With the achievements in science and technology in the past twenty years an increasing number of injectables apply prefilled syringes. The benefits compared with vial-disposable syringe concepts are obviously convenience and ease of handling as well as advantages in safety and a reduction of drug overfill
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Developments in the packaging of pre-filled syringes
The pre-filled syringe is an increasingly attractive presentation for both new and established parenteral pharmaceuticals and vaccines. In this article, the author explores how innovative carton packaging solutions can enhance this presentation whilst meeting the stringent requirements of both product protection and environmental sustainability. He analyses recent developments in the packaging …
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Ketorolac: a review of its pharmacodynamic and pharmacokinetic properties and…
Ketorolac is a non-steroidal agent with potent analgesic and moderate antiinflammatory activity. It is administered as the tromethamine salt orally, intramuscularly, intravenously, and as a topical ophthalmic solution. Clinical studies indicate single-dose efficacy greater than that of morphine, pethidine (meperidine) and pentazocine in moderate to severe postoperative pain, with some evidence …
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Ketorolac tromethamine as compared with morphine sulfate for treatment of pos…
Ketorolac tromethamine, a nonnarcotic, prostaglandin synthesisinhibiting analgesic, was compared with morphine sulfate for relief of moderate to severe postoperative pain. The 155 patient participants received single intramuscular doses of either ketorolac, 10, 30, or 90 mg, or morphine, 6 or 12 mg, administered in a double-blind, randomized fashion. Pain scores (verbal and visual analog) were …
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Prefilled syringe: a review of injectable dosage form delivery system
Prefilled syringe are convenient device for the drug delivery of parental dosage form. There is easy to makes and delivering the precise dosage of the medication. The content of this review article is component of Prefilled syringe, application of Prefilled syringe, compatibility study of the drug product with the packing material, Extractable and leachable and challenge’s with the Prefilled …
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Comparison of intravenous ketorolac at three doses for treating renal colic i…
Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) that is extensively used for the management of renal colic in the emergency department (ED). It has been proposed that ketorolac is used at doses above its analgesic ceiling with no more advantages and increased risk of adverse effects. In this study, we compared the analgesic effects of three doses of intravenous ketorol…
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Single dose oral analgesics for acute postoperative pain in adults - an overv…
We identified systematic reviews in the Cochrane Database of Systematic Reviews in The Cochrane Library through a simple search strategy. All reviews were overseen by a single review group, had a standard title, and had as their primary outcome the number of participants with atleast 50% pain relief overfourto six hours compared with placebo. Forindividualreviews, we extracted the number needed…
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Triamcinolone Acetonide Extended‑Release: A Review in Osteoarthritis Pain o…
Triamcinolone acetonide extended-release (ER) 32 mg (Zilretta®) is approved in the USA for the management of osteoarthritis (OA) pain of the knee and is administered as a single, 5 mL intra-articular (IA) injection. Although the therapeutic effects from IA corticosteroids are typically short-lived, triamcinolone acetonide ER is formulated in poly (lactic-co-glycolic acid) (PLGA) microsphere…
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