Management of Acquired Hemophilia: A Literature Review

Acquired hemophilia is a rare, but often severe, bleeding disorder caused by autoantibodies against a coagulation factor, usually factor VIII (FVIII). The most common clinical presentations are diffuse bruising, soft tissue bleeds, and hematuria

Updates in Hypertension Studies According to the Main Clinical Trials: A Revi…

High blood pressure remains one of the most important risk factors for cardiovascular disease. Although there is no consensus, all the clinical practice guidelines agree on the need to reduce blood pressure levels tominimize the risks. There aremany clinical trials conducted to try to find the best pharmacotherapy to achieve this goal. The aim was to compare the main international randomized c…

Medical Nutrition Therapy for Patients with None Dialysis-Dependent Chronic K…

CHRONIC KIDNEY DISEASE (CKD) currently affects approximately 15% of the US population or 30 million US adults,1 but incidence is projected to increase over the next 2 decades due to the ongoing obesity epidemic and the aging of the US population.2 Almost half of all US adults aged 65 years and older are predicted to develop CKD during their lifetime.2 The economic impact of CKD is substantial

Improved Myocardial Perfusion in Stable Angina Pectoris by Oral Lumbrokinase:…

This paper represents the first description of the use of oral lumbrokinase in the treatment of chronic coronary artery disease with objective assessment using MPI. Oral lumbrokinase improves regional myocardial perfusion in patients with stable angina.

Better with Ultrasound: Subclavian Central Venous Catheter Insertion

The Q2 insertion of a subclavian central venous catheter is generally associated with a high rate of success and a favorable risk profile. The use of ultrasound for procedural guidance has been demonstrated to further increase the rate of success and reduce the risk of specific mechanical complications, especially in patients with difficult surface anatomy

2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Manag…

Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health. These guidelines, which are based on systematic methods to evaluate and classify evidence, provide a cornerstone for quality cardiovascular care.

Efficacy of Oral Clonidine Premedication in Children

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Clinical Significance of Mitral Regurgitation After Acute Myocardial Infarction

Mitral regurgitation (MR) may complicate acute myocardial infarction (MI). However, it is not known whether mild MR is an independent predictor of post-MI outcome

PubMed Labs: an experimental system for improving biomedical literature search

PubMed is a freely accessible system for searching the biomedical literature, with ∼2.5 million users worldwide on an average workday. In order to better meet our users’ needs in an era of information overload, we have recently developed PubMed Labs (www.pubmed.gov/labs), an experimental system for users to test new search features/tools (e.g. Best Match) and provide feedback, which enables…

Interactive Web-based regional journal club for postgraduate year 2 pharmacy …

Participation in journal club presentations has been repeatedly demonstrated to develop therapeutic knowledge, increase awareness of current research, and enhance critical thinking skills.1,2 However, literature evaluation activities may prove challenging for student pharmacists and residents. For pharmacy preceptors, initiating and maintaining a regular and effective journal club can be diffic…