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Benefits and safety of candesartan treatment in heart failure are independent…
Ageing may affect drug efficacy and safety in patients with heart failure (HF). The Candesartan in Heart ailureAssessment of Reduction in Mortality and morbidity (CHARM) programme offered an opportunity to study the relationship between increasing age and the efficacy and safety of treatment in an uniquely broad spectrum of patients with symptomatic HF and either reduced or preserved left vent…
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Medication compliance and clinical outcomes of fixed-dose combinations vs fre…
Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free com‐ binations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medica…
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Effect of Amlodipine + Candesartan on Cardiovascular Events in Hypertensive P…
Combination therapy with calcium channel blockers and angiotensin II receptor blockers is recommended as one of the effective therapies for hypertension. However, it remains unclear whether this combination reduces major adverse cardiovascular events (MACEs) in patients with hypertension with coronary artery disease (CAD). The purpose of the present study was to examine the effects of amlod…
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