Cardiac characteristics in the premature ventricular contraction patients wit…

Background/Aims: Frequent (sustained) premature ventricular contractions (PVCs) lead to ventricular tachycardia (VT), which triggers ventricular fibrillation and sudden cardiac death. The cardiac characteristics and risk prediction in frequent/sustained PVC patients with or without VT have been still in need of investigation. Methods: The data from patients with frequent PVCs via 24 h ambulator…

Nephrotic syndrome in children

Nephrotic syndrome is an important chronic disease in children, characterized by minimal change disease in the majority. Research on pathogenesis has emphasized the importance of T lymphocyte dysregulation and vascular permeability factors that might alter podocyte function and permselectivity. While mutations in genes that encode important podocyte proteins have also been identified, a hypoth…

Nephrotic Syndrome

Nephrotic syndrome is a disorder of the kidneys that results from increased permeability of the glomerular filtration barrier. It is characterized by 4 major clinical characteristics that are used in establishing the diagnosis: proteinuria, hypoalbuminemia, edema, and hyperlipidemia. This article reviews nephrotic syndrome in the pediatric population, with special attention paid to minimal chan…

Effects of candesartan and amlodipine on cardiovascular events in hypertensiv…

We examined the effects of candesartan and amlodipine on cardiovascular events in hypertensive patients with chronic kidney disease (CKD) using the data from the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial. CKD was defined as proteinuria and/or decreased GFR (o60 ml per min per 1.73m2) at enrollment. Among 2720 subjects with CKD, there were 1376 and 1344 patients…

Treatment of Severe Diphtheritic Myocarditis by Temporary Insertion of a Card…

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The Quest for New Approaches in Myocarditis and Inflammatory Cardiomyopathy

Myocarditis is a diverse group of heart-specific immune processes classified by clinical and histopathological manifestations. Up to 40% of dilated cardiomyopathy is associated with inflammation or viral infection. Recent experimental studies revealed complex regulatory roles for several microribonucleic acids and T-cell and macrophage subtypes.

Clinical Features and Predictors of Diphtheritic Cardiomyopathy in Vietnamese…

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Migraine and risk of cardiovascular diseases: Danish population based matched…

To examine the risks of myocardial infarction, stroke (ischaemic and haemorrhagic), peripheral artery disease, venous thromboembolism, atrial fibrillation or atrial flutter, and heart failure in patients with migraine and in a general population comparison cohort.

Cardiovascular outcomes associated with canagliflozin versus other non-gliflo…

To evaluate the cardiovascular safety of canagliflozin, a sodium-glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes mellitus, in direct comparisons with DPP-4 inhibitors (DPP-4i), GLP-1 receptor agonists (GLP-1RA), or sulfonylureas, as used in routine practice.

Cancer risk associated with chronic diseases and disease markers: prospective…

To assess the independent and joint associations of major chronic diseases and disease markers with cancer risk and to explore the benefit of physical activity in reducing the cancer risk associated with chronic diseases and disease markers