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Long-term management of gastroesophageal refl ux disease with pantoprazole
Gastroesophageal refl ux disease (GERD) is a chronic, relapsing disease that can progress to major complications. Affected patients have poorer health-related quality of life than the general population. As GERD requires continued therapy to prevent relapse and complications, most patients with erosive esophagitis require long-term acid suppressive treatment. Thus GERD results in a signifi …
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Pharmacokinetics of Pantoprazole in Patients with Moderate and Severe Hepatic…
Patients with impaired hepatic function usually require gastric acid suppressant therapy but are at increased risk for drug interactions and may require dosage adjustments. The proton pump inhibitor pantoprazole is rapidly absorbed and eliminated, primarily by cytochrome P450 (CYP) 2C19 isozymes.
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Drug-Drug Interaction Profiles of Proton Pump Inhibitors
Proton pump inhibitors (PPIs) are widely prescribed for the treatment of gastric acid-related disorders and the eradication of Helicobacter pylori. In addition, they are routinely prescribed for the prevention of gastrointestinal bleeding in patients receiving a dual antiplatelet therapy consisting of clopidogrel and aspirin (acetylsalicylic acid) after myocardial infarction or percutaneous cor…
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Efficacy and safety of proton pump inhibitors and H2 receptor antagonists in …
The present network meta‑analysis aimed to enhance the corresponding evidence with respect to the efficacy and safety of pharmaceuticals treatments. Frequentist network meta‑analysis was used. Medical literature up to November 2022 was searched for randomized clinical trials assessing the efficacy and safety of these pharmaceuticals, either compared with each other or compared with placebo.…
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Efficacy of pantoprazole plus perforation repair for peptic ulcer and its eff…
Peptic ulcer (PU) is an abnormal phenomenon in which there is rupture of the mucosa of the digestive tract, which not only affects patients' normal life but also causes an economic burden due to its high medical costs
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Patient Diagnosis Resource for RADIATION COLITIS
Your doctor has determined that you have radiation colitis, an inflammation of the colon that occurs as a side effect of cancer radiation therapy to the abdomen or pelvis. The condition can arise from external radiation treatment delivered by a high energy X-ray machine or internal radiation therapy, which is delivered through small implants placed directly into or near the cancerous tumor
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