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Severe Complications of Bronchoscopy
Bronchoscopy is a widely performed procedure that is generally considered to be safe and effective. In recent years, the flexible bronchoscope has been refined, and its range of applications has been greatly expanded [1] , which has led to an increase in the complication rate in our hospital
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Empyema thoracis
The actual incidence of empyema thoracis is still increasing worldwide and remains a clinical challenge with significant impact on public health; early recognition and prompt evaluation are of prime importance. Despite a lack of standardization of treatments, management should be planned according to stage, avoiding delays on referral
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Empyema Thoracis
Epmyema thoracis is associated with high mortality ranging between 6% to 24%. The incidence of empyema is increasing in both children and adults; the cause of this surge is unknown. Most cases of empyema complicate community- or hospital-acquired pneumonia but a proportion results from iatrogenic causes or develops without pneumonia
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Sexuality in patients with asthma and COPD
Sexual quality of life was examined in 55 outpatients with chronic obstructive pulmonary disease (COPD) and asthma, using disease-specific questionnaires. Compared to an ageand sex-matched norm group, male patients with COPD reported a significantly lower sexual quality of life on all dimensions of the questionnaire.
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Asthma and Sex
Attacks of asthma can be provoked by a variety of stimuli, including infections, allergens, exercise, and emotional stress. Sexual intercourse as a trigger factor for attacks of asthma and the morbidity caused thereof is not well recognized
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An algorithm recommendation for the pharmacological management of allergic rh…
Allergic rhinitis is a frequent presenting problem in primary care in the UK, and has increased in prevalence over the last 30 years. When symptomatic, patients report significant reduction in their quality of life and impairment in school and work performance. Achieving adequate symptom control is pivotal to successful allergic rhinitis management, and relies mostly on pharmacotherapy. Whil…
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SERPINA1 Gene Variants in Granulomatosis with Polyangiitis
Alpha-1 antitrypsin (A1AT) deficiency is one of the most common genetic disorders in Caucasian population. There is a link between granulomatosis with polyangiitis (GPA) and most frequent variants of SERPINA1 gene encoding severe alpha-1 antitripsin deficiency
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SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency
Alpha-1-antitrypsin (AAT) deficiency is a genetic disorder that produces inactive/defective AAT due tomutations in the SERPINA1 gene encoding AAT. This disease is associated with decreased activity of AAT in the lungs and deposition of excessive defective AAT protein in the liver. Currently there is no specific treatment for liver disease associated with AAT deficiency. AAT lung disease is o…
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Chronic Cough and Gastroesophageal Reflux in Children: CHEST Guideline and E…
Whether gastroesophageal reflux (GER) or GER disease (GERD) causes chronic cough in children is controversial. Using the Population, Intervention, Comparison, Outcome (PICO) format, we undertook four systematic reviews. For children with chronic cough (> 4-weeks duration) and without underlying lung disease: (1) who do not have gastrointestinal GER symptoms, should empirical treatment for GERD …
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A practical guide to transthoracic ultrasound
Transthoracic ultrasonography is a well-established, yet underutilised imaging modality in respiratory medicine. It allows for real-time and mobile assessment of thoracic disorders and can potentially augment the physical examination of the chest. Moreover, ultrasonography-assisted interventions can be performed by a single clinician without sedation and with minimal monitoring, even outside o…
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