Necrotizing fasciitis: Classification, diagnosis, and management

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Protection of dexmedetomidine against ischemia/reperfusion-induced apoptotic …

Dexmedetomidine, an agonist of alpha2-adrenergic receptors, is used for critically ill patients to induce and maintain sedation and analgesia. Brain ischemia/reperfusion (I/R) usually causes severe neuronal injuries to intensive care unit patients. This study was aimed to evaluate the effects of dexmedetomidine on I/R-induced insults to neuronal cells and the possible mechanisms. Treatment of n…

Diagnosis and Treatment of Perilymphatic Fistula

Perilymphatic fistula (PLF) is defined as an abnormal communication between the fluid perilymph)-filled space of the inner ear and the air-filled space of the middle ear and mastoid, or cranial spaces. PLF is located in the round or oval window, fractured bony labyrinth, icrofissures, anomalous footplate, and can occur after head trauma or barotrauma, chronic inflammation, or in otic capsule …

A review on uric acid in plants and microorganisms: Biological applications a…

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The protective effects of dexmedetomidine on ischemic brain injury: A meta-an…

Intracranial lesions, traumaor surgery-related damage activate immune inflammation and neuroendocrine responses, causing ischemic brain injury. Studies have shown that inflammatory cascade mediated by neuroendocrine hormones and proinflammatory mediators is implicated in the pathophysiology of ischemic brain injury. Alpha2-adrenoceptor agonists, dexmedetomidine, is widely used as neuroprotec…

Does dexmedetomidine offer brain protection?

Since the introduction of dexmedetomidine into clinical practice, the potent alpha2 agonist has been used in a variety of settings and for an increasing number of indications. The drug is a selective agonist to the alpha2-adreno-receptor subtype (alpha2-AR ). The alpha2-AR is widely distributed in the nervous system and in most peripheral tissues.

Neck pain (cervical syndrome)

Pain can radiate in an imprecisely defi ned way into the back of the head, forehead, neck, shoulders and upper arms.

Sclerostin

TheWnt signaling pathway demonstrates a complex network of proteins well known for their roles in embryogenesis but also involving normal physiologic processes of bone formation in response to loading and unloading

Sclerostin: Current Knowledge and Future Perspectives

In recent years study of rare human bone disorders has led to the identification of important signaling pathways that regulate bone formation. Such diseases include the bone sclerosing dysplasias sclerosteosis and van Buchem disease, which are due to deficiency of sclerostin, a protein secreted by osteocytes that inhibits bone formation by osteoblasts.

Management of traumatic perilymph fistula with endoscopic techniques

These images relate to a 13-year-old boy who sustained a traumatic perilymph fistula (tPLF) resulting from a skateboarding accident.