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Multidisciplinary OBGYN morbidity and mortality conference
Obstetrics and gynecology (OB-GYN) morbidity and mortality conferences allow for review of cases with poor or avoidable outcomes. Little data exist on standardized formats for presentation and evaluation. We designed a multidisciplinary morbidity and mortality conference. We formally evaluated resident performance using the milestones format, and evaluated resident understanding of case concep…
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Assessment of quality of care among in-patients with postpartum haemorrhage a…
The maternal mortality ratio of Uganda is still high and the leading causes of maternal mortality are postpartum haemorrhage (PPH), severe pre-eclampsia and eclampsia. Criteria-based audit (CBA) is a way of improving quality of care that has not been commonly used in low income countries. This study aimed at finding out the quality of care provided to patients with these conditions and to find …
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Mechanisms of action of intrauterine devices: Update and estimation of postfe…
There are many potential mechanisms of action for the intrauterine device (IUD), which vary by type of IUD (inert, copper, or hormonal). This paper reviews the evidence for each potential mechanism of action. On the basis of available data for fertilization rates and clinical pregnancy rates, the relative contribution of mechanisms acting before or after fertilization were quantitatively estima…
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Intrauterine Devices: An Update
Three intrauterine devices (IUDs) are available in the United States: the copper T 380A and two levonorgestrel-releasing IUDs, one that releases 20 mcg of levonorgestrel per 24 hours, and one that releases 14 mcg per 24 hours. All are safe and effective methods of contraception that work predominantly by prefertilization mechanisms. The copper T 380A IUD may be placed in nonpregnant women at an…
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Time for OBGYNs to Care for People of All Genders
There are at least 1.5 million transgendera individuals (0.5% by a household population based survey) in the United States.1 Although transgender individuals are often closeted, marginalized, and maligned there is growing social, political, and medical awareness. In June 2014, actress Laverne Cox became the first openly transgender person to be on the cover of Time Magazine
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OBGYN screening for environmental exposures: A call for action
Prenatal exposures have known adverse effects on maternal and neonatal outcomes. Professional societies recommend routine screening for environmental, occupational, and dietary exposures to reduce exposures and their associated sequelae.
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Adaptive immunity
The innate immune system provides critical mechanisms for the rapid sensing and elimination of pathogens. Adaptive immunity has evolved to provide a broader and more finely tuned repertoire of recognition for both self- and nonself-antigens. Adaptive immunity involves a tightly regulated interplay between antigen-presenting cells and T and B lymphocytes, which facilitate pathogen-specific immu…
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Natural Antibodies Bridge Innate and Adaptive Immunity
Natural Abs, belonging to isotypes IgM, IgG3, and IgA, were discovered nearly half a century ago. Despite knowledge about the role of the polyreactive natural IgM in pathogen elimination, B cell survival and homeostasis, inflammatory diseases, and autoimmunity, there is a lack of clarity about the physiological role of natural IgG and natural IgA because they appear incapable of recognizing Ag…
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Analysis of IL-6, IL-10, IL-17 levels in the blood of patients with chronic h…
To investigate the role and significance of serum IL-6, IL-10, IL-17 in the occurrence and development of chronic hepatitis B. Methods: Enzyme-linked immunosorbent assay (ELISA) was used to detect serum IL-6, IL-10, IL-17 levels and liver function in patients with hepatitis B and relationship between serum viral load in 70 cases of CHB patients and 20 healthy subjects (control group)
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