The present study was designed to explore the mechanisms involved in the anti-ischemic action of lumbrokinase (LK) in brain. The enzyme immunoassay, spectrofluorimeter and flow cytometry were used to detect the level of adenosine 3′,5′-cyclic monophosphate (cAMP) and guanosine 3′,5′-cyclic monophosphate (cGMP), the Ca2+ mobilization, and human platelet surface antigen expression in o…
Atherosclerosis is a multifactorial and dynamic process. One of the early features of atherosclerosis is the presence of fatty streaks along the vessel wall. These fatty streaks are characterized by accumulation of lipid-filled smooth muscle cells and macrophages and fibrous tissue in focal areas of the intima
HE diagnosis and treatment of pulmonary embolism demand an interdisciplinary approach, combining medical, surgical, and radiologic specialties. Despite substantial advances, mortality and recurrence rates remain high.