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Differential effects of the charge variants of human follicle-stimulating hor…
FSH is synthesized and secreted by the anterior pituitary gland in multiple molecular forms; the release of these isoforms depends on the endocrine status of the donor at the time of sample collection. In the present study, we analysed the possibility that the FSH charge isoforms may exert differential effects at the target cell. Seven FSH isoform mixes were isolated from pooled anterior pituit…
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Simultaneous administration of human acidic and recombinant less acidic folli…
Ovarian stimulation is an integral procedure in assisted reproduction treatment. It is achieved by the administration of exogenous gonadotropins to increase follicular recruitment and oocyte yield. Optimization of ovarian stimulation is an essential prerequisite for the success of IVF treatment.
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Senyum Cerah di Hari Raya : Tips Menjaga Kesehatan Gigi di Tengah Sajian Manis
Hari Raya identik dengan aneka kue kering, minuman manis, dan hidangan spesial yang sulit ditolak. Di tengah momen kebersamaan dan silaturahmi, penting bagi kita tetap menjaga kualitas kesehatan gigi agar senyum tetap percaya diri. Mari luangkan waktu sejenak untuk investasi kesehatan diri. Karena senyum sehat membuat silaturahmi terasa semakin hangat dan bermakna.
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Knowledge Sharing Session : Sosialisasi Pengisian SPT Tahunan Karyawan Melalu…
Dalam rangka meningkatkan pemahaman karyawan terhadap sistem pelaporan pajak terbaru, tim Corporate Training & Development bekerjasama dengan Corporate Remuneration & HRIS, dan Corporate Tax, telah menyelenggarakan kegiatan Sharing Knowledge bertajuk “Sosialisasi Penginputan SPT Tahunan Melalui Coretax, 13 Februari 2026 lalu. Kegiatan ini dilakukan secara online zoom diikuti oleh sejumlah kar…
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Effects of Dexmedetomidine-Remifentanil on Neurodevelopment of Children after…
Anesthetic exposure in young children raises concerns about neurodevelopmental safety, with preclinical evidence suggesting potential neurotoxicity of volatile anesthetics. This study aimed to assess whether the combination of dexmedetomidine and remifentanil, by reducing sevoflurane exposure, has any differential effect on neurodevelopmental outcomes in young children compared with sevoflurane…
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Exforge® (amlodipine/valsartan combination) in hypertension: the evidence of…
This review analyses one of these strategies, which is the development of effective and safe combination therapy. Indeed, at least two antihypertensive agents are often needed to achieve blood pressure control. Exforge® (Novartis) is a new drug combination of the calcium channel blocker, amlodipine, and the angiotensin II receptor blocker, valsartan
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Pharmacokinetic and bioequivalence of two formulations of Valsartan/Amlodipin…
Valsartan/amlodipine combination tablets can exert synergistic antihypertensive effects through different mechanisms, significantly lowering blood pressure while also addressing multiple risk factors and comorbidities in patients. This study designed a single-center, randomized, open-label, two-formulations, single-dose, three-cycle, three-sequence, partially repeated crossover controlled trial…
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Valsartan addition to amlodipine is more effective than losartan addition in …
This study evaluated the effects on blood pressure (BP) of valsartan 160 mg or losartan 100 mg addition to amlodipine 5 mg in hypertensive patients.
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Improved Persistence to Medication, Decreased Cardiovascular Events and Reduc…
Antihypertensive combination therapy reduces all-cause mortality and cardiovascular events when provided as single pill compared to identical drugs as multipills. This strongly supports the European Society of Cardiology/European Society of Hypertension and International Society of Hypertension guidelines recommending the use of a single-pill combination and thus should be more rigorously imple…
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Real-Life Safety and Effectiveness of Amlodipine/Valsartan Combination in the…
The aim of our study was to evaluate the safety and effectiveness of the free combination of amlodipine/valsartan in patients with arterial hypertension in a real-life setting
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